Protein Alignment Arp5 and ARP5

DIOPT Version :9

• Sequence 1: NP_001262697.1
• Gene: Arp5 / 42173
• FlyBaseID: FBgn0038576
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_014339.1
• Gene: ARP5 / 855665
• SGDID: S000005004
• Length: 755
• Species: Saccharomyces cerevisiae
• Alignment Length: 735
• Identity: 203/735 - (27%)
• Similarity: 355/735 - (48%)
• Gaps: 120/735 - (16%)

  Fly     7 LVIDNGSYECRVGWSDSKEPDLRFRNVLTKPRKDRKKEAAASEGSASQTTVEQSAEIQVGNDITN 71
            :.||.||.:.|.|:.:...|...|.|.|||.| |||.....:               .||||...
Yeast    40 IAIDFGSSKLRAGFVNHATPTHIFPNALTKFR-DRKLNKNFT---------------FVGNDTLL 88

  Fly    72 IEAVRAHLKSPFERNVITNWNHQEQIFDYIFTKMGFDGQDKIDHPIILTEALANPNFCRQQMNEL 136
            .:|||:..:|||:...:||||..|:|.||.|..:|....:.|.:||:|||.||.....|....::
Yeast    89 DQAVRSQSRSPFDGPFVTNWNLTEEILDYTFHHLGVVPDNGIPNPILLTERLATVQSQRTNWYQI 153

  Fly   137 LFECYGIPSVSYGIDALYSWKHHQQKQKNISDALIISFGYSTTHVIPVLDGKLQLEHVRRLNVGG 201
            |||.|.:|.|::|||:|:|:.::.....  ...|:||.|:..|:||||:||...|...:|:|.||
Yeast   154 LFETYNVPGVTFGIDSLFSFYNYNPSGN--KTGLVISCGHEDTNVIPVVDGAGILTDAKRINWGG 216

  Fly   202 YHIITYLFRLMQMKYPVHLNAITISRMEKLVHEHCHIAVDYKEELVQWAQMDYYDEHIMKIQLPY 266
            :..:.||..||.:|||.....::..:.|.:..::|:::.:|.|::.:...::..|.:.:.::.|:
Yeast   217 HQAVDYLNDLMALKYPYFPTKMSYLQYETMYKDYCYVSRNYDEDIEKILTLENLDTNDVVVEAPF 281

  Fly   267 NAVTATNAMLTAEQ---KQEKRRELAHRLLDIKKNREQEKLREDEQQLFVYNKLR-QLYEQKK-- 325
            ..|  .....|.|:   :.|||:|...||.:..:.:..|||.:.:::...::|:| ||.::.|
Yeast   282 TEV--LQPQKTEEELRIQAEKRKETGKRLQEQARLKRMEKLVQKQEEFEYFSKVRDQLIDEPKKK 344

  Fly   326 -------------------LDKFERALQQQQIGTLEDLDSLIATIN------------------- 352
                               |...|::|::.|:...|| ||.:..:|
Yeast   345 VLSVLQNAGFDDERDFKKYLHSLEQSLKKAQMVEAED-DSHLDEMNEDKTAQKFDLLDIADEDLN 408

  Fly   353 ------SRIKRAQERAQSGPRPSKQQ-ERLNKMPKPPEGMSQA-------DWLAELQGKREKILG 403
                  .|.:|..:.:|...:.:|:: ||:.|..:..:...|.       .|:.:.:.|..|::.
Yeast   409 EDQIKEKRKQRFLKASQDARQKAKEEKERVAKEEEEKKLKEQQWRETDLNGWIKDKRLKLNKLIK 473

  Fly   404 RKQARQQQRSEQAKRHTHAAQERMRIISSLAKNEKRRKAN--------GEEEDDGFGMNDNDWDV 460
            |::.:.:.|.|...|.:..:|.||:.::|||::..::.|.        ..:.:|.||.||.||.:
Yeast   474 RRKEKLKLRDEMKDRKSQVSQNRMKNLASLAEDNVKQGAKRNRHQATIDNDPNDTFGANDEDWLI 538

  Fly   461 YKRINRYNDDSDSDA---DNEKLMQFDKILNHYDANTDGNSNVPPQ------------------- 503
            |..|.: |.::..:|   :.:.:::.:::|..:|.|......:..|
Yeast   539 YTDITQ-NPEAFEEALEYEYKDIVELERLLLEHDPNFTEEDTLEAQYDWRNSILHLFLRGPRPHD 602

  Fly   504 --SAAENYQLHFGVENIRVPEVLFQPSMIGCSEAGLAELI-AFVLKLF---PAAEQQR---LVEH 559
              :..|.:|:|..||.||||||:|||:|.|..:||:.||. ..:||.|   |....|.   :|.:
Yeast   603 SENIHEQHQMHLNVERIRVPEVIFQPTMGGQDQAGICELSETILLKKFGSQPGKLSQTSIDMVNN 667

  Fly   560 VYLTGGCAQFKGLKERLIKELMEMRPFQSKFAIYESDEPTLSAWLG-ACVHAGEPTFGQTLTTRQ 623
            |.:|||.|:..|||||::||.....|..:...:..|.:|:|.||.| |.:...|..:.:|:.:::
Yeast   668 VLITGGNAKVPGLKERIVKEFTGFLPTGTNITVNMSSDPSLDAWKGMAALARNEEQYRKTVISKK 732

  Fly   624 DHQEHGREFFREHTASNIFY 643
            :::|:|.|:.:||...|..|
Yeast   733 EYEEYGPEYIKEHKLGNTKY 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp5	NP_001262697.1	COG5277	1..637	CDD:227602	200/727 (28%)
ARP5	NP_014339.1	COG5277	33..>358	CDD:227602	102/337 (30%)
		PRK00409	<292..428	CDD:234750	27/136 (20%)
		NBD_sugar-kinase_HSP70_actin	<536..748	CDD:418402	62/212 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343071
Domainoid	1	1.000	121	1.000	Domainoid score	I1248
eggNOG	1	0.900	-	-		E1_KOG0681
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6818
Inparanoid	1	1.050	267	1.000	Inparanoid score	I611
Isobase	1	0.950	-	1	Normalized mean entropy	S3096
OMA	1	1.010	-	-		QHG54909
OrthoFinder	1	1.000	-	-		FOG0005644
OrthoInspector	1	1.000	-	-		oto99528
orthoMCL	1	0.900	-	-		OOG6_104278
Panther	1	1.100	-	-	LDO	PTHR11937
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R84
SonicParanoid	1	1.000	-	-		X4046
TreeFam	1	0.960	-	-
	16	15.740