DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cdm and AT1G12930

DIOPT Version :9

Sequence 1:	NP_001262696.1	Gene:	cdm / 42171	FlyBaseID:	FBgn0261532	Length:	971	Species:	Drosophila melanogaster
Sequence 2:	NP_563920.1	Gene:	AT1G12930 / 837851	AraportID:	AT1G12930	Length:	1005	Species:	Arabidopsis thaliana

Alignment Length:	982	Identity:	197/982 - (20%)
Similarity:	387/982 - (39%)	Gaps:	179/982 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RLEEAV-VSFYRSNSQNQAITHEWLTDAEASPQAWQFSWQLM--QLGKSQEVQFFGAITLHSKLM 69
            ::.||: |..:...|.|:...::||...:.:|.||..|..|:  .:....::|||.|..|..|:.
plant     6 KVAEAIHVLNHDPESSNRVAANQWLVQFQLTPAAWDVSTSLLTSPIVSLFDLQFFAAQILRRKIQ 70

  Fly    70 KHWHEVPPENREELKQKILESIVRFAGGPKIVLNRLCISLGAYIVHMLGEWPGAIEEVINTFQNQ 134
            .....:....::.|...:|.:..|::.|...:|.::|::|.|.::|. ..:....::::...||.
plant    71 NEASNLQSTAKDALLNALLLAAKRYSSGVPQLLTQICLALSALLLHS-DPYSKPFDKLMFALQNL 134

  Fly   135 RM---PNVSADVQLWIMLEVLTAIPEEAQVIHTSVKRVVLRAEIAKRVQLVIHTVERYLKLQMNR 196
            :.   .||       ::||:||.:|||............||.|:.....:|:.    :|..|...
plant   135 QAHDDGNV-------VLLELLTVLPEEISDTRHFSHHSDLRQELLSHTSMVLD----FLLQQSEN 188

  Fly   197 VWDAEAY--SNMNRAVKCVGTWIKNIGYTIEGC---VTITAV----LLEVVHKCYWPCIHAGDGC 252
            .:.:..|  .|..:.::|:.:|::      .||   :...||    ||..|
plant   189 QFVSPLYPHDNNRKILRCLLSWVR------AGCFSEIPQGAVPSHPLLNYV-------------- 233

  Fly   253 MTADENELAESCLKTMVNIIIQPDCHNYPKTAFVLIKMFLDSLSEITKTEWKRENDNEDI-IVHI 316
            ..|.:....:..::.:|.::.:.:  :.|:.....::...|:|       .|....|.|: |:..
plant   234 FNALQGTTFDLAIEVLVELVTRHE--DLPQVLLYKVQFLRDTL-------LKPALINADLKIISG 289

  Fly   317 YMLFVSSVERHSTLLLSGITSADPELSILVHRIVQEILHCTDKPGIYPVEE-SCSTMALAFWYML 380
            ....:|.:.:.:..|   |..|..|..||    ...||.|.    .:|.|: ..:...:.||...
plant   290 LACLMSEIGQAAPCL---IVEASSEALIL----TDAILSCV----TFPSEDWEIADSTVQFWSTF 343

  Fly   381 QDEVFAMSNDEQ--KHKCWEYIKPLYAHLTRILVRKSEQPDEKSLAKWSSDDLECFRCYRQDISD 443
            ...:.::..:.|  :.:..:...|:::.|...||.:: |.||.:    |||:....     |:.|
plant   344 ATYILSLGGNRQNDRTRVKDTFLPVFSALVDALVLRA-QVDEFT----SSDESPGL-----DLPD 398

  Fly   444 TFMYCYDVLNDYILEILAAMLDEAIADLQRHPTHWT------------------KLEACIYSFQS 490
            ..::..:.|.:.:::|...:          |||.:.                  ::||.:::..:
plant   399 GLLHFRNNLLELLVDICQLL----------HPTTFVSKLFFGGVPSSSVSMPLREIEAKLFALTA 453

  Fly   491 VAEHF--GGE--EKRQIPRLMRVLAEIPYEKLN--VKLLGTAL-ETMGSYCNWLMENPAYIPPAI 548
            |:|..  .||  :...|.:|:...:..|..:|.  :.::..:| :.:|||..|:...|:...|.:
plant   454 VSEIILQEGEAFDFALIMQLVSAFSVRPSSELKGFISVVYRSLADVVGSYSRWISVFPSNARPLL 518

  Fly   549 NLLVRGLNSSMSAQA-TLGLKELCRDCQLQLKPYAD-PLLNACHASLNTGRMKNSDSVRLMFSIG 611
            ..|..|::..:.:.| ...|:::|.|....::..:: .:|......|....:...|...::.:|.
plant   519 LFLAGGISEPICSHACASALRKICEDAPAVIQETSNLDILMWIGECLEQWDLTLEDEEEVITAIT 583

  Fly   612 KLMSLLRPEEIP-KYLDIIVSPCFEELQAICQADS-----KTPAARIRTIFR----LNMISTLFS 666
            .::..:..:|:. |.|..::|..:..|..:...|:     ::||...|.:..    |..|.|:||
plant   584 VILGSVANKELQNKLLTQLLSSSYGVLSKLVDEDAESSGRQSPATYTRMLSSVTRGLYRIGTVFS 648

  Fly   667 SLNTDVDEQATDQPIVQ----PVLLVMQRTMPIFKRI-AEMWVEEIDVLEAACSAMKHAITNLRS 726
            .|       ||..|.|.    |:|.::....||.::: ....:|...:..|||.|:..|:.:...
plant   649 HL-------ATSLPSVPVADGPILSLLTVFWPILEKLFRSEHMESGSLAAAACRALSVAVQSSGE 706

  Fly   727 SFQPMLQDL--CL---FIVASFQTRCCAPTLEISKTAIVM---FFKDEGCKPLMQQLLREFIQHS 783
            .|..:|..:  ||   |:  |||::.|     ..:||.|:   |...|....|.......|.|.|
plant   707 HFMLLLPSVLDCLSRNFL--SFQSQEC-----YIRTACVIAEEFCHKEEYGSLFITTFERFTQAS 764

  Fly   784 FKLFESTPEQNFSNI----SDTMETFFGCLTQIIKKIPQVLEDKTLAYDRLVFY-AQRGMTLPES 843
                 |....|.|.|    .|.:|.:....:.:|:...:.|...:.....:.|: |....|....
plant   765 -----SLMGINSSYICDQEPDLVEAYVNFASALIRSCHKELLGTSGTLLEISFHKAAICCTAMHR 824

  Fly   844 GAIRNSIQFLTHFVMQSRNHAHVT--------------EVVLATGEQTLYTAMMCVGYLTPRSQV 894
            ||...::.:|:.|:..|.:....|              :||...||..|...:..:..:...|:|
plant   825 GAALAAMSYLSGFLEVSLSSMIETVNSISDGSFSVVSVQVVSHCGEGLLSNLVYALLGVAAMSRV 889

  Fly   895 DKFADIL 901
            .|.:.||
plant   890 HKCSTIL 896

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cdm	NP_001262696.1	IBN_N	28..92	CDD:281761	15/65 (23%)
cdm	NP_001262696.1	Xpo1	98..>217	CDD:285575	25/123 (20%)
AT1G12930	NP_563920.1	Xpo1	118..249	CDD:369848	29/161 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004114
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12363
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.870