DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment cdm and CG10950

DIOPT Version :10

Sequence 1:NP_650682.1 Gene:cdm / 42171 FlyBaseID:FBgn0261532 Length:971 Species:Drosophila melanogaster
Sequence 2:NP_611200.2 Gene:CG10950 / 36942 FlyBaseID:FBgn0034205 Length:586 Species:Drosophila melanogaster


Alignment Length:686 Identity:122/686 - (17%)
Similarity:257/686 - (37%) Gaps:185/686 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 NSQNQAITHEWLTDAEASPQAWQFSWQLMQLGKSQEVQF--FGAITLHSKLMKHWHEVPPENREE 82
            :|.|.::.:|:|...:.|...|..:.:::......::..  |.|::|..|:...::.:.......
  Fly    18 SSGNISLANEYLAAFQKSNDTWIIAEEILSYRPPHDMHILTFAAMSLAKKIKTSFYSLQKFQLMS 82

  Fly    83 LKQKILESIVRFAG---GPKIVLNRLCISLGAYIVHMLGEWPGAIEEVINTFQNQRMPNVSADVQ 144
            ||..:::.: ::|.   ....::.:|.:.:.| :..|..:|...:::.:.        .:|.:.|
  Fly    83 LKNSLIDHL-KYAAMMRDSNSLIVQLAVGISA-LGLMFSQWDYELQDFVR--------KLSENPQ 137

  Fly   145 -LWIMLEVLTAIPEEAQVIHTSVKRVVLRAEIAKRVQLVIHTVERYLKLQMNRVWDAEAYSNMNR 208
             :..:||||..||||.:..:..|:        ||::..||.|:|:    |...:.|         
  Fly   138 YVMALLEVLKVIPEETRPSNLPVE--------AKKLNSVIDTLEQ----QSPYILD--------- 181

  Fly   209 AVKCVGTWIKNIGYTIEGCVTITAVLLEVVHKCYWPCIHAGDGCMTADENELAESCLKTMVNIII 273
                          .:||.:....:..:.:.||...|.......|.:.:..|..........|:.
  Fly   182 --------------VLEGLLQRPDLPDDALPKCLAVCASWTKFSMLSPDQVLQRKLFIMAEFILA 232

  Fly   274 QPDCHNYPKTAFVLIKMFLDSL--SEIT----------KTEWKRENDNEDIIVHIYMLFVSSVER 326
            .|..:.:.:.|.:.:.:...||  .|:.          |..:||......::.:...:||:..:.
  Fly   233 TPLVNGHLEAAELFVALLEQSLIRKELNSCLANSVICLKPAFKRSMGERSLLQNYCNIFVNLFQT 297

  Fly   327 HSTLLLSGITSADPELSILVHRIV--QEILHCTDKPGIYPVEESCSTMALAFWYMLQDEVFAMSN 389
            |..|     |..:||.  |..|:|  :.:|...::..:..:|.|     |..|..:.:||: :.:
  Fly   298 HFRL-----TQTNPER--LNERLVTIELLLLVAEESPLEVIEAS-----LGMWSSISEEVY-LHD 349

  Fly   390 DEQKHKCWEYIKPLYAHLTRILVRKSEQP-DEKSLAKWSSDDLECFRCYRQDISDTFMYCYDVLN 453
            |.:.:..::   |.:..|..:|:.::..| :.:.:....|.|::.||              :::.
  Fly   350 DPEMYSVYQ---PYFVRLLDLLLPRAALPANYEFMMPPGSADMQRFR--------------ELIG 397

  Fly   454 DYILEILAAMLDE--------AIADLQRHPTHWTKLEACIYSFQSVAEHFGGEEKRQIPRLMRVL 510
            :.:|: :|.|:|:        .:.|.|   :.|.::||.::..:.:..:|...:...|..:::..
  Fly   398 EVLLD-MAHMIDDDTVEKLCSIVVDEQ---SPWMEVEASVFFLRHLIGNFKEHQTDIISCILKTF 458

  Fly   511 ----AEIPYEKLNVKLLGTALETMGSYCNWLMENPAYIPPAINLLVRGLNSSMSAQATLGLKELC 571
                .:.|:.:|.|      ||.:.            ||..:::                  |..
  Fly   459 FQKDCQQPFIRLQV------LELIS------------IPEIVSV------------------ETI 487

  Fly   572 RDCQLQLKPYADPLLNACHASLNTGR-----------------MKNSDSVRLMFSIGKLMSLLRP 619
            .||.:.....|||:|:|....||...                 :|.|:...|:.||   .:|:| 
  Fly   488 WDCLVNELRRADPMLSAIDCRLNLLMPHWNYLVTLAIMVDEFCLKESERCELLCSI---CTLIR- 548

  Fly   620 EEIPKYLDIIVSPCFEELQAICQADSKTPAARIRTI 655
                            ||.|.|..::||....||.|
  Fly   549 ----------------ELPAACVQEAKTSILNIRWI 568

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cdmNP_650682.1 IBN_N 29..93 CDD:197981 10/65 (15%)
Xpo1 98..>220 CDD:462459 23/122 (19%)
Importin_rep 418..454 CDD:436727 5/36 (14%)
Importin_rep_3 838..912 CDD:465873
CG10950NP_611200.2 IBN_N 25..91 CDD:197981 10/65 (15%)
Xpo1 103..>207 CDD:462459 28/147 (19%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.