DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wrd and AT3G21650

DIOPT Version :9

Sequence 1:	NP_732295.1	Gene:	wrd / 42169	FlyBaseID:	FBgn0042693	Length:	984	Species:	Drosophila melanogaster
Sequence 2:	NP_001326520.1	Gene:	AT3G21650 / 821719	AraportID:	AT3G21650	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	579	Identity:	268/579 - (46%)
Similarity:	357/579 - (61%)	Gaps:	77/579 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   302 KSPVSAAAAIKNILNATKSVGTSAAAAAAAAATSSSSSPSSAAAVPSSAATAVAAVPTTSDVPAE 366
            |.|...:.:::|..|....|..|  ..|:.::|:|.|.|||.::..|||:.:..|
plant     8 KLPRKPSKSLQNDSNGEGGVNNS--YYASNSSTTSISKPSSTSSKSSSASGSRVA---------- 60

  Fly   367 EMRPTVAQNLVGGISISLGIGQRNGGAAPASSAVMVTPNATMVVTTSSLSIRQN---GDILPGHP 428
                                   ||..||                 :|:|..:|   |....|..
plant    61 -----------------------NGTLAP-----------------NSMSSNRNTNQGKKPLGGD 85

  Fly   429 AGLQPSPQTLQQLTGSPGRARDRNLFYTPPTASVAMALPALRETAASEREELFIQKIQQCCTLFD 493
            |.:|..|                    .|.:..|..|||:.|:...||:..|||.|:..||.:||
plant    86 AVVQAGP--------------------FPSSGGVYEALPSFRDVPISEKPNLFIGKLSMCCVVFD 130

  Fly   494 FSEPLSDLKFKEVKRAALHEMVDFLTNQNGVITEVIYPEAINMFAVNLFRTLPPSSNPNG--AEF 556
            ||:|..:||.||:||..|.|:||::.:......:|...|...|.|||||||.|.:::.:.  ...
plant   131 FSDPSKNLKEKEIKRQTLLELVDYVASVGFKFNDVSMQELTKMVAVNLFRTFPSANHESKILEIH 195

  Fly   557 DPEEDEPTLESSWPHLQLVYELFLRFLESPDFQPSMAKRFIDHQFVLQLLDLFDSEDPRERDFLK 621
            |.:::||:||.:|||:|:|||:.|||:.||.....:|||:|||.|||:|||||||||.|||::||
plant   196 DMDDEEPSLEPAWPHVQVVYEILLRFVASPMTDAKLAKRYIDHSFVLKLLDLFDSEDQREREYLK 260

  Fly   622 TVLHRIYGKFLGLRAFIRKQINNVFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKQFLL 686
            |:|||:||||:..|.:|||.|||:|||||.|||.|||||||||||||||||||||||||||.|||
plant   261 TILHRVYGKFMVHRPYIRKAINNIFYRFISETEKHNGIAELLEILGSIINGFALPLKEEHKLFLL 325

  Fly   687 KVLLPLHKAKSLSVYHPQLTYCVVQFLEKDPSLSEAVIKSLLKFWPKTHSPKEVMFLNELEELLD 751
            :.|:||||.|..||||.||:||:|||:|||..|::.||:.|||:||.|:|.||||||.||||:|:
plant   326 RALIPLHKPKCSSVYHQQLSYCIVQFVEKDFKLADTVIRGLLKYWPVTNSSKEVMFLGELEEVLE 390

  Fly   752 VIEPAEFQKVMVPLFRQIAKCVSSPHFQVAERALYYWNNEYIMSLITDNSAVILPIMFPALNRNS 816
            ..:.||||:.||||.||||:|::|.|||||||||:.|||::|.:|||.|..||:||:||||.||:
plant   391 ATQAAEFQRCMVPLSRQIARCLNSSHFQVAERALFLWNNDHIRNLITQNHKVIMPIVFPALERNT 455

  Fly   817 KTHWNKTIHGLIYNALKLFMEIDQRLFDECSKNYKQEKQMEREKLSQREELWQQVESLA 875
            :.|||:.:..|..|..|:..||||.|||||...::.|:..:.|..::||..||::|.||
plant   456 RGHWNQAVQSLTINVRKVLCEIDQVLFDECLAKFQVEEVNKTEVKAKRERTWQRLEDLA 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrd	NP_732295.1	B56	474..875	CDD:279883	231/402 (57%)
wrd	NP_732295.1	PLN00122	<780..879	CDD:215064	48/96 (50%)
AT3G21650	NP_001326520.1	B56	58..>122	CDD:421517	24/133 (18%)
AT3G21650	NP_001326520.1	B56	110..514	CDD:396263	231/403 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	507	1.000	Domainoid score	I70
eggNOG	1	0.900	-	-		E1_KOG2085
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D890437at2759
OrthoFinder	1	1.000	-	-		FOG0000226
OrthoInspector	1	1.000	-	-		mtm982
orthoMCL	1	0.900	-	-		OOG6_100293
Panther	1	1.100	-	-	O	PTHR10257
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X167
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.780