DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wrd and ATB' BETA

DIOPT Version :9

Sequence 1:	NP_732295.1	Gene:	wrd / 42169	FlyBaseID:	FBgn0042693	Length:	984	Species:	Drosophila melanogaster
Sequence 2:	NP_187599.1	Gene:	ATB' BETA / 820146	AraportID:	AT3G09880	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	495	Identity:	256/495 - (51%)
Similarity:	344/495 - (69%)	Gaps:	36/495 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   383 SLGIGQRNGGAAPASSAVMVTPNATMVVTTSSLSIRQNGDILPGHPAGLQPSPQTLQQLTGSPGR 447
            |.|||..:..:.|.|:.|:...:...:|.:|                   |||     :|.:|.
plant    23 SYGIGLPDNRSGPGSNVVVSHASRGALVNSS-------------------PSP-----VTATPP- 62

  Fly   448 ARDRNLFYTPPTASVAMALPALRETAASEREELFIQKIQQCCTLFDFSEPLSDLKFKEVKRAALH 512
                    .||..||. .||..|:...|||:.||::|:|.||.||||::.:.:.:.||:||..|.
plant    63 --------PPPLGSVE-PLPLFRDVPVSERQTLFLRKLQNCCFLFDFTDTIKNARDKEIKRQTLL 118

  Fly   513 EMVDFLTNQNGVITEVIYPEAINMFAVNLFRTLPPSSNPN-GAE-FDPEEDEPTLESSWPHLQLV 575
            |:|||:.:.:..|:|....|.|.|.:||:||:|||:|:.| |.| .||||:||.||.||||||||
plant   119 ELVDFIQSGSSKISESCQEEMIKMISVNIFRSLPPASHENTGQEPADPEEEEPYLEPSWPHLQLV 183

  Fly   576 YELFLRFLESPDFQPSMAKRFIDHQFVLQLLDLFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRK 640
            |||.||::.|.|....:|||:|||.|||:|||||||||||||::|||:||||||||:..|.||||
plant   184 YELLLRYVVSTDTDTKVAKRYIDHSFVLKLLDLFDSEDPREREYLKTILHRIYGKFMVHRPFIRK 248

  Fly   641 QINNVFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKQFLLKVLLPLHKAKSLSVYHPQL 705
            .|||:|||||||||.|:||.||||||||||||||||:|||||.||::||:||||.|.:.|||.||
plant   249 AINNIFYRFIYETERHSGIGELLEILGSIINGFALPMKEEHKLFLIRVLIPLHKPKPIVVYHQQL 313

  Fly   706 TYCVVQFLEKDPSLSEAVIKSLLKFWPKTHSPKEVMFLNELEELLDVIEPAEFQKVMVPLFRQIA 770
            :||:|||:|||..|::.||:.|||:||.|:..||.:||.||||:|:..:|.|||:.|||||:||.
plant   314 SYCIVQFVEKDYKLADTVIRGLLKYWPVTNCSKENLFLGELEEVLEATQPVEFQRCMVPLFQQIG 378

  Fly   771 KCVSSPHFQVAERALYYWNNEYIMSLITDNSAVILPIMFPALNRNSKTHWNKTIHGLIYNALKLF 835
            :|::|.|||||||||:.||||:|:.||..|.:|||||::|.|.:|.::|||:.:|||..|..|:|
plant   379 RCLTSSHFQVAERALFLWNNEHIVGLIAQNRSVILPIIYPTLEKNIQSHWNQAVHGLTTNIKKMF 443

  Fly   836 MEIDQRLFDECSKNYKQEKQMEREKLSQREELWQQVESLA 875
            ||:|..||:||.:.|::::...:|...||:..|:::...|
plant   444 MEMDPELFEECQRQYEEKQAKSKEVEEQRQYTWKRLAEAA 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrd	NP_732295.1	B56	474..875	CDD:279883	234/402 (58%)
wrd	NP_732295.1	PLN00122	<780..879	CDD:215064	44/96 (46%)
ATB' BETA	NP_187599.1	B56	29..>91	CDD:421517	22/95 (23%)
ATB' BETA	NP_187599.1	B56	79..483	CDD:396263	234/403 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	507	1.000	Domainoid score	I70
eggNOG	1	0.900	-	-		E1_KOG2085
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D890437at2759
OrthoFinder	1	1.000	-	-		FOG0000226
OrthoInspector	1	1.000	-	-		mtm982
orthoMCL	1	0.900	-	-		OOG6_100293
Panther	1	1.100	-	-	LDO	PTHR10257
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X167
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.780