Protein Alignment wrd and Ppp2r5d

DIOPT Version :10

• Sequence 1: NP_732295.1
• Gene: wrd / 42169
• FlyBaseID: FBgn0042693
• Length: 984
• Species: Drosophila melanogaster
• Sequence 2: XP_006244632.1
• Gene: Ppp2r5d / 363193
• RGDID: 1306666
• Length: 672
• Species: Rattus norvegicus
• Alignment Length: 743
• Identity: 397/743 - (53%)
• Similarity: 475/743 - (63%)
• Gaps: 144/743 - (19%)

  Fly   296 SSIAASKSPVSAAAAIKNI------LNATKSVGTSAAAAA----AAAATSSSSSPSSAAAVPSSA 350
            |.:|...:|......::.:      |.|...:|..||...    |..|....:.|.......|.|
  Rat     6 SCLAPMTNPRRRRLVVRQVCKSSGQLEAQPPLGPGAARRRWRRDAERAECGRAEPEPERGRRSRA 70

  Fly   351 ATAVAAVPTTSDVPAEEMRPTVAQNLVGGISISLGIGQRNGGAAPASSAVMVTPNATMVVTTSSL 415
            ....|.:|.......:| .|.:|:                |.|.|:||:
  Rat    71 GCGPAEMPYKLKKDKQE-PPKLAK----------------GTAKPSSSS---------------- 102

  Fly   416 SIRQNGDILPGHPAGLQPSPQTLQQLTGSPGRARDRNLFYTPPTASVA----------------- 463
              :..|.......|..||.||        |..:..|....|||...::
  Rat   103 --KDGGGENTDTEAQPQPQPQ--------PPSSNKRPSNSTPPPTQLSKIKYSGGPQIVKKERRQ 157

  Fly   464 -------------MALPALRETAASEREELFIQKIQQCCTLFDF-SEPLSDLKFKEVKRAALHEM 514
                         ..||||:::...|||||||||::|||.|||| |:|||||||||||||.|:||
  Rat   158 SSSRFNLSKNRELQKLPALKDSPTQEREELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEM 222

  Fly   515 VDFLTNQNGVITEVIYPEAINMFAVNLFRTLPPSSNPNGAEFDPEEDEPTLESSWPHLQLVYELF 579
            |:::|:...|:||.|||||:.||:|||||||||||||.||||||||||||||::|||||||||.|
  Rat   223 VEYITHSRDVVTEAIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFF 287

  Fly   580 LRFLESPDFQPSMAKRFIDHQFVLQLLDLFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINN 644
            |||||||||||::||::||.:|||.||||||||||||||||||:|||||||||||||:||:|||:
  Rat   288 LRFLESPDFQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQINH 352

  Fly   645 VFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKQFLLKVLLPLHKAKSLSVYHPQLTYCV 709
            :|||||||||||||||||||||||||||||||||||||.||::|||||||.||||||||||.|||
  Rat   353 IFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLHKVKSLSVYHPQLAYCV 417

  Fly   710 VQFLEKDPSLSEAVIKSLLKFWPKTHSPKEVMFLNELEELLDVIEPAEFQKVMVPLFRQIAKCVS 774
            ||||||:.||:|.||..||||||||||||||||||||||:||||||:||.|||.|||||:|||||
  Rat   418 VQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFRQLAKCVS 482

  Fly   775 SPHFQVAERALYYWNNEYIMSLITDNSAVILPIMFPALNRNSKTHWNKTIHGLIYNALKLFMEID 839
            |||||||||||||||||||||||:||:|.:||||||||.||||:|||||||||||||||||||::
  Rat   483 SPHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPALYRNSKSHWNKTIHGLIYNALKLFMEMN 547

  Fly   840 QRLFDECSKNYKQEKQMEREKLSQREELWQQVESLAKTNPEWTKARRFNDCLPVSDSRALCDQYS 904
            |:|||:|::.||.|||..|.::.:|||:||::|.||:.||::...|
  Rat   548 QKLFDDCTQQYKAEKQKGRFRMKEREEMWQKIEELARLNPQYPMFR------------------- 593

  Fly   905 ENSDSAYDQSEQRARQPPPPLPP---------------------QKQAHQEPREIRGERNKDKPL 948
                            .||||||                     :.:|.|..::|:    |||.|
  Rat   594 ----------------APPPLPPVYSMETETPTAEDIQLLKRTVETEAVQMLKDIK----KDKVL 638

  Fly   949 LRRKSDLPSDSGTVKALNEHKRTDEYLT 976
            |||||:||.|..|:|||..|||.:|:||
  Rat   639 LRRKSELPQDVYTIKALEAHKRAEEFLT 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wrd	NP_732295.1	B56	475..875	CDD:460264	323/400 (81%)
Ppp2r5d	XP_006244632.1	B56	126..>192	CDD:474937	16/65 (25%)
		B56	180..583	CDD:460264	323/402 (80%)