Protein Alignment wrd and Ppp2r5c

DIOPT Version :9

• Sequence 1: NP_732295.1
• Gene: wrd / 42169
• FlyBaseID: FBgn0042693
• Length: 984
• Species: Drosophila melanogaster
• Sequence 2: XP_006515987.1
• Gene: Ppp2r5c / 26931
• MGIID: 1349475
• Length: 606
• Species: Mus musculus
• Alignment Length: 616
• Identity: 372/616 - (60%)
• Similarity: 453/616 - (73%)
• Gaps: 49/616 - (7%)

  Fly   382 ISLGIGQRNGGAAPASSAVMVTPNATMVVTTSSLSIRQNGDILPGHPAGLQPSPQTLQQLTGSPG 446
            :..|.|.:.|.....:.......:.|:|.:::|..|:     :|.....:.|..:..:|.:....
Mouse    15 VKSGKGPKEGQDTAETEIASRKNSLTVVQSSTSTKIK-----VPIPQPVVVPVKKDKRQNSSRFN 74

  Fly   447 RARDRNLFYTPPTASVAMALPALRETAASEREELFIQKIQQCCTLFDF-SEPLSDLKFKEVKRAA 510
            .:.:|.|          ..||:|::...:::|:|||||::|||.|||| |:||||||:|||||||
Mouse    75 ASNNREL----------QKLPSLKDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAA 129

  Fly   511 LHEMVDFLTNQNGVITEVIYPEAINMFAVNLFRTLPPSSNPNGAEFDPEEDEPTLESSWPHLQLV 575
            |.|||:::|:...||||.|||||::|||||:||||||||||.||||||||||||||::|||||||
Mouse   130 LSEMVEYITHNRNVITEPIYPEAVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLV 194

  Fly   576 YELFLRFLESPDFQPSMAKRFIDHQFVLQLLDLFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRK 640
            ||.||||||||||||::||::||.:||||||:|||||||||||||||.|||||||||||||:|||
Mouse   195 YEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRK 259

  Fly   641 QINNVFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKQFLLKVLLPLHKAKSLSVYHPQL 705
            ||||:|||||||||||||||||||||||||||||||||||||.|||||||||||.||||||||||
Mouse   260 QINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQL 324

  Fly   706 TYCVVQFLEKDPSLSEAVIKSLLKFWPKTHSPKEVMFLNELEELLDVIEPAEFQKVMVPLFRQIA 770
            .||||||||||.:|:|.|:.:|||:||||||||||||||||||:||||||:||.|:|.|||||:|
Mouse   325 AYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLA 389

  Fly   771 KCVSSPHFQVAERALYYWNNEYIMSLITDNSAVILPIMFPALNRNSKTHWNKTIHGLIYNALKLF 835
            |||||||||||||||||||||||||||:||:|.|||||||:|.||||||||||||||||||||||
Mouse   390 KCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLF 454

  Fly   836 MEIDQRLFDECSKNYKQEKQMEREKLSQREELWQQVESLAKTNPEW----------------TKA 884
            ||::|:|||:|::.:|.||..|:.|:.:|||.|.::|:|||.||::                |..
Mouse   455 MEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASAVSIPVAMETDG 519

  Fly   885 RRFNDC----LPVSDSRALCDQYSENSDSAYDQSEQRARQPPPPLPPQKQAHQEPREIRGERNKD 945
            .:|.|.    ..|||.........|.|..::...|.         .....|.|..:|::    ||
Mouse   520 PQFEDVQMLKKTVSDEARQVKVGREKSHDSHASQEG---------VETDWAAQAQKELK----KD 571

  Fly   946 KPLLRRKSDLPSDSGTVKALNEHKRTDEYLT 976
            :||:||||:||.|..|.|||..|.|..|.|:
Mouse   572 RPLVRRKSELPQDPHTEKALEAHCRASELLS 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wrd	NP_732295.1	B56	474..875	CDD:279883	321/401 (80%)
		PLN00122	<780..879	CDD:215064	71/98 (72%)
Ppp2r5c	XP_006515987.1	B56	91..494	CDD:366725	321/402 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847467
Domainoid	1	1.000	691	1.000	Domainoid score	I134
eggNOG	1	0.900	-	-		E1_KOG2085
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	731	1.000	Inparanoid score	I612
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D345293at33208
OrthoFinder	1	1.000	-	-		FOG0000226
OrthoInspector	1	1.000	-	-		otm42353
orthoMCL	1	0.900	-	-		OOG6_100293
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3
SonicParanoid	1	1.000	-	-		X167
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.690