Protein Alignment wrd and pptr-2

DIOPT Version :9

• Sequence 1: NP_732295.1
• Gene: wrd / 42169
• FlyBaseID: FBgn0042693
• Length: 984
• Species: Drosophila melanogaster
• Sequence 2: NP_001122845.1
• Gene: pptr-2 / 179526
• WormBaseID: WBGene00007554
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 641
• Identity: 340/641 - (53%)
• Similarity: 426/641 - (66%)
• Gaps: 87/641 - (13%)

  Fly   349 SAATAVAAVPT--TSDV-----PAEEMRPTVAQNLVGGISISLGIGQRNG-GAAPASSAVMVTPN 405
            :.::..:.:||  |.||     ||:...||             .||:.|. |..|      |.|.
 Worm    31 AGSSKASTIPTIRTEDVGGDMIPADAPPPT-------------NIGRTNTYGGGP------VIPR 76

  Fly   406 ATMVVTTSSLSIRQNGDILPGHPAGLQPSPQTLQQLTGSPGRARDRNLFYTPPTASVAMALPALR 470
            .....::|..:|.||.::                                        ..|||::
 Worm    77 RERRQSSSMFNISQNREL----------------------------------------QRLPAIK 101

  Fly   471 ETAASEREELFIQKIQQCCTLFDF-SEPLSDLKFKEVKRAALHEMVDFLTN-QNGVITEVIYPEA 533
            :...||||.|||||::|||.:||| ::.||||||||||||||:|:||.::. ..|.:::.:||||
 Worm   102 DADPSERETLFIQKLRQCCVVFDFANDALSDLKFKEVKRAALNELVDHVSGAPKGSLSDAVYPEA 166

  Fly   534 INMFAVNLFRTLPPSSNPNGAEFDPEEDEPTLESSWPHLQLVYELFLRFLESPDFQPSMAKRFID 598
            |.||:.||||.|.|.:||.||||||:|||||||::|||||||||.||||||.||||..:|||:||
 Worm   167 IGMFSTNLFRPLSPPTNPIGAEFDPDEDEPTLEAAWPHLQLVYEFFLRFLECPDFQSQVAKRYID 231

  Fly   599 HQFVLQLLDLFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNVFYRFIYETEHHNGIAELL 663
            ..|:|:||.:.|||||||||||||.||||||||||.||:|||||||:||.||||||.||||||||
 Worm   232 QNFILRLLMIMDSEDPRERDFLKTTLHRIYGKFLGHRAYIRKQINNIFYSFIYETERHNGIAELL 296

  Fly   664 EILGSIINGFALPLKEEHKQFLLKVLLPLHKAKSLSVYHPQLTYCVVQFLEKDPSLSEAVIKSLL 728
            |||||||||||||||||||.|||:|||||||.||||||||||.||||||:|||.||:|.||..:|
 Worm   297 EILGSIINGFALPLKEEHKTFLLRVLLPLHKVKSLSVYHPQLAYCVVQFIEKDSSLTEPVISGML 361

  Fly   729 KFWPKTHSPKEVMFLNELEELLDVIEPAEFQKVMVPLFRQIAKCVSSPHFQVAERALYYWNNEYI 793
            :||||.||||||||||||||:||||||.||||:|.|||.|||:|||||||||||||||||||||:
 Worm   362 RFWPKQHSPKEVMFLNELEEVLDVIEPNEFQKIMTPLFSQIARCVSSPHFQVAERALYYWNNEYV 426

  Fly   794 MSLITDNSAVILPIMFPALNRNSKTHWNKTIHGLIYNALKLFMEIDQRLFDECSKNYKQEKQMER 858
            |||:.||:.||:|||||.|.:|||:|||||||||||||||:|||::|:||||||:.|::::..|:
 Worm   427 MSLVADNARVIIPIMFPVLFKNSKSHWNKTIHGLIYNALKMFMEMNQKLFDECSQAYQKDRVQEK 491

  Fly   859 EKLSQREELWQQVESLAKTNPEWTKAR----RFNDCLPVSDSRALCDQYSENSDSAYDQSEQRAR 919
            ....::|.:|..:|..|..||::.:.:    |||....:|..:.  :...||..::...|:....
 Worm   492 TLNEEKERIWNNIEKQAMGNPQYVEVKALFARFNPDEIISSRQQ--NGVDENMKTSTVLSKDEIL 554

  Fly   920 QPPPPLPPQKQAHQEPREIRGERNKDKPLLRRKSDLPSDSGTVKALNEHKRTDEYL 975
            :....:...|            .:.|.....::||.|.|..|.:||.|:||.|.:|
 Worm   555 KNAVGVSSMK------------NDMDFGPNHKQSDFPPDEQTTRALGEYKRHDPFL 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wrd	NP_732295.1	B56	474..875	CDD:279883	293/402 (73%)
		PLN00122	<780..879	CDD:215064	60/98 (61%)
pptr-2	NP_001122845.1	B56	105..508	CDD:279883	293/402 (73%)
		PLN00122	<413..508	CDD:215064	59/94 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165252
Domainoid	1	1.000	627	1.000	Domainoid score	I84
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37661
Inparanoid	1	1.050	642	1.000	Inparanoid score	I439
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D345293at33208
OrthoFinder	1	1.000	-	-		FOG0000226
OrthoInspector	1	1.000	-	-		oto18153
orthoMCL	1	0.900	-	-		OOG6_100293
Panther	1	1.100	-	-	LDO	PTHR10257
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3
SonicParanoid	1	1.000	-	-		X167
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.930