DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wrd and ppp2r5b

DIOPT Version :9

Sequence 1:	NP_732295.1	Gene:	wrd / 42169	FlyBaseID:	FBgn0042693	Length:	984	Species:	Drosophila melanogaster
Sequence 2:	NP_001093749.1	Gene:	ppp2r5b / 100101792	XenbaseID:	XB-GENE-490177	Length:	491	Species:	Xenopus tropicalis

Alignment Length:	505	Identity:	285/505 - (56%)
Similarity:	367/505 - (72%)	Gaps:	38/505 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   423 ILPGHPA--GLQP----------SPQTLQQL------TGSPGRARDRNLFYTPPTASVAMALPAL 469
            :.|..|:  ||.|          |.::|::.      :.|..|.:.:....||        ||.|
Frog     7 VTPTSPSSPGLSPVLAADKVDGFSRRSLRRSRQRRSHSSSQFRYQSKQQELTP--------LPPL 63

  Fly   470 RETAASEREELFIQKIQQCCTLFDFSEPLSDLKFKEVKRAALHEMVDFLTNQNGVITEVIYPEAI 534
            ::...||..:||.:|:|||..:|.|.:.::|||.||:|||||:|:|:.:....||:.|.:|||.|
Frog    64 KDAPVSELHDLFCKKLQQCSVIFQFMDCVADLKGKEIKRAALNELVECIATNRGVLIEPVYPEVI 128

  Fly   535 NMFAVNLFRTLPPSSNPNGAEFDPEEDEPTLESSWPHLQLVYELFLRFLESPDFQPSMAKRFIDH 599
            .|.:||:||||||:.||   |||||||||..|.||||||||||.|||||||.|||||:|||::|.
Frog   129 KMISVNIFRTLPPTDNP---EFDPEEDEPNFEPSWPHLQLVYEFFLRFLESQDFQPSLAKRYVDQ 190

  Fly   600 QFVLQLLDLFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNVFYRFIYETEHHNGIAELLE 664
            :|||.||:||||||||||::|||:|||:|||||||||:||||.||:|.|||||||..||:|||||
Frog   191 KFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNNIFLRFIYETERFNGVAELLE 255

  Fly   665 ILGSIINGFALPLKEEHKQFLLKVLLPLHKAKSLSVYHPQLTYCVVQFLEKDPSLSEAVIKSLLK 729
            ||||||||||||||.||||||::||:|||.|||||::|.||.||.|||||||.||:|.||:.|||
Frog   256 ILGSIINGFALPLKSEHKQFLVRVLIPLHSAKSLSIFHAQLAYCAVQFLEKDSSLTEHVIRGLLK 320

  Fly   730 FWPKTHSPKEVMFLNELEELLDVIEPAEFQKVMVPLFRQIAKCVSSPHFQVAERALYYWNNEYIM 794
            :||||.:.||||||.||||:||||||::|.|:..|||:|||:|||||||||||||||:||||||:
Frog   321 YWPKTCTQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIARCVSSPHFQVAERALYFWNNEYIL 385

  Fly   795 SLITDNSAVILPIMFPALNRNSKTHWNKTIHGLIYNALKLFMEIDQRLFDECSKNYKQEKQMERE 859
            |||.:|...|||::|..|.:.||.|||:||..||||.||.|||::.:||||.:.:||.::|.|.:
Frog   386 SLIEENCHTILPLIFGTLYQVSKEHWNQTIVSLIYNVLKTFMEMNGKLFDELTASYKLDRQQEMK 450

  Fly   860 KLSQREELWQQVESLAKTNPEWTKARRFNDCLPVSDSRALCDQYSENSDS 909
            :..:|:|||::::.|        :.::.|. |..:....|..|:|..|.|
Frog   451 REKERQELWRKLDDL--------RLKKMNG-LEEAQMNQLNLQHSRGSKS 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrd	NP_732295.1	B56	474..875	CDD:279883	263/400 (66%)
wrd	NP_732295.1	PLN00122	<780..879	CDD:215064	51/98 (52%)
ppp2r5b	NP_001093749.1	B56	67..465	CDD:366725	263/400 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D345293at33208
OrthoFinder	1	1.000	-	-		FOG0000226
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3
SonicParanoid	1	1.000	-	-		X167
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950