Protein Alignment CG7218 and TAPT1

DIOPT Version :10

• Sequence 1: NP_650678.1
• Gene: CG7218 / 42165
• FlyBaseID: FBgn0038569
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_699196.2
• Gene: TAPT1 / 202018
• HGNCID: 26887
• Length: 567
• Species: Homo sapiens
• Alignment Length: 552
• Identity: 237/552 - (42%)
• Similarity: 336/552 - (60%)
• Gaps: 71/552 - (12%)

  Fly    58 GSAQQRLQSG-----TAETCTNT--FYD------------------FFKVEMTRGYMLEHDEERY 97
            |.|:|...||     .|...|.|  ||:                  |...|:||||.|||:|.:|
Human    27 GEAEQPGGSGGQGPPPAPQLTETLGFYESDRRRERRRGRTELSLLRFLSAELTRGYFLEHNEAKY 91

  Fly    98 SARRQKIYSFMRIPRDLERFMVYGIMQCADSFLYIHTFLPVRFVMAVWALVSRTVARIFRLRSSG 162
            :.||:::|:.:||||:||:.||:||..|.|:|||:.|.||:|..:|::.|::   ...:.||.
Human    92 TERRERVYTCLRIPRELEKLMVFGIFLCLDAFLYVFTLLPLRVFLALFRLLT---LPCYGLRD-- 151

  Fly   163 QRLLSPAEICDLLKGVIWMTVTLIMLLVDTNRVYHIIKSQSIIKLYIFYNMLEVGDRLLSAFGQD 227
            :|||.||::||:|||||.:....:|..||.:.:||:|:.||:|||||.||||||.|||.|:||||
Human   152 RRLLQPAQVCDILKGVILVICYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQD 216

  Fly   228 TIDALFWTATEPKNSKREHFGVLTHVLFTLIYVFLHSGLIMFQATCLNVAVNSNNKGLLTIMISN 292
            .:|||:|||||||..||.|.||:.|....::|||||:.|||.|||.||||.||:||.|||||:||
Human   217 ILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSN 281

  Fly   293 NFVELKGSVFKKFDKNNLFQLTCSDVRERFHLSVLLFIVVIQTMKEFDWSITQFCVMLPDCFAVL 357
            ||||:||||||||:||||||::.||::|||...|||.||.::.|::|.|:.....|:.||...|:
Human   282 NFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIVCLRNMEQFSWNPDHLWVLFPDVCMVI 346

  Fly   358 FTEILIDWVKHAFITRFNELPESIYREYTTSLAYDMTQTRQKHAFSDHSDLVARRMGFIPFPLAV 422
            .:||.:|.|||||||:||::...:|.||..|||:|:..:|||:|::|:||.|||||||||.||||
Human   347 ASEIAVDIVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVARRMGFIPLPLAV 411

  Fly   423 VLIKAIYTAVSFENLAAWLLFLLAYLFAMGLRICLTICALGKACKLMKEHQTERNSSTPSSMTNV 487
            :||:.:.:::..:.:.::...:|.|...:.|::..:|..|||:|:.:||.:.|...|.|
Human   412 LLIRVVTSSIKVQGILSYACVILFYFGLISLKVLNSIVLLGKSCQYVKEAKMEEKLSNP------ 470

  Fly   488 PVIGAAAPVSAAATGGQNHNNNNN----------NNNNSISIGSKPAQ---------VTT----L 529
                     .|..|.|:..:.:.|          ..|.|.||..:|..         ||:    .
Human   471 ---------PATCTPGKPSSKSQNKCKPSQGLSTEENLSASITKQPIHQKENIIPLLVTSNSDQF 526

  Fly   530 LTPPSAGHLDVSKNFSRTSIASTSTPKKAVSE 561
            ||.|.....|::::.|.....|:   ||.:.|
Human   527 LTTPDGDEKDITQDNSELKHRSS---KKDLLE 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7218	NP_650678.1	DUF747	166..470	CDD:398815	163/303 (54%)
TAPT1	NP_699196.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..60		10/32 (31%)
		DUF747	155..459	CDD:398815	163/303 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	466..499		6/47 (13%)