Protein Alignment CG7218 and F26F2.7

DIOPT Version :9

• Sequence 1: NP_001287385.1
• Gene: CG7218 / 42165
• FlyBaseID: FBgn0038569
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_001355520.1
• Gene: F26F2.7 / 180347
• WormBaseID: WBGene00009172
• Length: 714
• Species: Caenorhabditis elegans
• Alignment Length: 637
• Identity: 226/637 - (35%)
• Similarity: 361/637 - (56%)
• Gaps: 71/637 - (11%)

  Fly     4 TLNSAGGKRQLRFRGDVTGSRVEE-------LHHQQQEEQKQKAPLAQDDVAATPTATPAAGSAQ 61
            |..|.|.:|:|..: |..||.:|.       :....:....::..:..|...::|........:|
 Worm    66 TPKSTGIRRRLTLK-DSIGSDLENDPESTPAIRKPSRISYDERLTVICDSQTSSPLLAETPSPSQ 129

  Fly    62 QRLQSGTAETC-TNTFYDFFKVEMTRGYMLEHDEERYSARRQKIYSFMRIPRDLERFMVYGIMQC 125
            :|..:..|:.. ...|:.||..|:||||.|.:|..|:|.:|:|:|:|:|||.:||:|:.||::||
 Worm   130 ERDSAPFADVFQPKGFFSFFWEELTRGYSLHNDHARFSEKRRKVYAFLRIPLELEQFLTYGLLQC 194

  Fly   126 ADSFLYIHTFLPVRFVMAVWALVSRTVARIFRLRSSGQRLLSPAEICDLLKGVIWMTVTLIMLLV 190
            .|:|.|:.||||:||:|:::.    .:.||.|..|        ||.||.||.||.:..::::..:
 Worm   195 IDAFFYLFTFLPLRFLMSIFG----ALLRIKRWTS--------AETCDFLKVVIIVAASMLIREI 247

  Fly   191 DTNRVYHIIKSQSIIKLYIFYNMLEVGDRLLSAFGQDTIDALFWTATEPKNSKREHFGVLT--HV 253
            |::.:||.::||.:||||||||||||.|||.|:.|||..|||.|||...|.....:| :.|  |:
 Worm   248 DSSFLYHQVRSQGVIKLYIFYNMLEVADRLFSSLGQDIFDALLWTANSEKRFSVGYF-IRTCGHL 311

  Fly   254 LFTLIYVFLHSGLIMFQATCLNVAVNSNNKGLLTIMISNNFVELKGSVFKKFDKNNLFQLTCSDV 318
            :..::|..|||.|::.|||.||||.||:|:.:|.||:|||||||||||||||.|.||||:.||||
 Worm   312 IVAILYATLHSFLVILQATTLNVAFNSHNQTVLAIMMSNNFVELKGSVFKKFAKANLFQMACSDV 376

  Fly   319 RERFHLSVLLFIVVIQTMKEFDWSITQFCVMLPDCFAVLFTEILIDWVKHAFITRFNELPESIYR 383
            |||||:..|||:|:|:.|...:|:|..|..|:||...|:..|..:||:||||||:|||:...:|:
 Worm   377 RERFHIFALLFVVMIRNMTAVNWNIDSFTEMIPDIIMVVGCEYFVDWLKHAFITKFNEINAEVYK 441

  Fly   384 EYTTSLAYDMTQTRQKHAFSDHSDLVARRMGFIPFPLAVVLIKAIYTAVSFENLAAWLLFLLAYL 448
            ::|.::|:|:.::|.:.||||:||.|:|||||||.||::::|:.:....:.:|..:.::|.:.:|
 Worm   442 DFTITIAFDVIRSRDQSAFSDYSDQVSRRMGFIPIPLSIMIIRVLSQTFTLDNWGSCIIFGIGWL 506

  Fly   449 FAMGLRICLTICALGKAC---------------KLMKEHQTERNSSTPSSMTNVPVIGAAAPVSA 498
            ....::||..:..||:||               :|.::...|:.|.:..:...:.:|.....:..
 Worm   507 LVFAVKICNGVVMLGQACHHVKRFRDIQARAEFELFRKRMVEKKSKSAPNSPRMSLIDFTDVLHQ 571

  Fly   499 AATGGQNHNNNNNNNNNSISIGSKPAQVTTLLT-----PPSAGHLDVSKNFSR-------TSIAS 551
            .|.|                   |...|:.:|:     .||....::.::..|       |:.:.
 Worm   572 PAAG-------------------KGFTVSDMLSQWEELQPSLLSSEIRRSTDRETAVSHLTARSD 617

  Fly   552 TSTPKKAVSEQELDVTNSLE-LGATALFSNSDVDLDDVCLNEQVTNTNTSSA 602
            ..||::|||...:...:..| ..|.::..:..:|.:|..:.|..||:|:..|
 Worm   618 ERTPRRAVSMAHIPRRDRSEPPPAPSMDQDPQLDTEDPVVTENNTNSNSEQA 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7218	NP_001287385.1	DUF747	166..470	CDD:283096	146/320 (46%)
F26F2.7	NP_001355520.1	DUF747	223..528	CDD:310151	146/313 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167006
Domainoid	1	1.000	306	1.000	Domainoid score	I742
eggNOG	1	0.900	-	-		E1_KOG2490
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80206
Inparanoid	1	1.050	393	1.000	Inparanoid score	I1129
Isobase	1	0.950	-	0	Normalized mean entropy	S2841
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004082
OrthoInspector	1	1.000	-	-		oto19254
orthoMCL	1	0.900	-	-		OOG6_101942
Panther	1	1.100	-	-	LDO	PTHR13317
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1479
SonicParanoid	1	1.000	-	-		X2830
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.730