DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sr and egr3

DIOPT Version :9

Sequence 1:NP_001262693.1 Gene:sr / 42162 FlyBaseID:FBgn0003499 Length:1271 Species:Drosophila melanogaster
Sequence 2:NP_001002647.1 Gene:egr3 / 436920 ZFINID:ZDB-GENE-040718-394 Length:422 Species:Danio rerio


Alignment Length:378 Identity:148/378 - (39%)
Similarity:183/378 - (48%) Gaps:98/378 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   767 SPPSNSLGNS-WGLPSPDKTMFQPPLFSLPAHYATMQQQQQQQQQQQQQQQQQQAAGAAPSPYDD 830
            :|||.|:|.| |   .||..     :.||.:                     ....|.:|||   
Zfish    94 TPPSGSIGGSGW---CPDNN-----IISLVS---------------------AGILGVSPSP--- 126

  Fly   831 GRAAAAAAAQHAELLGLTMDCTPLLLKQPP-PSYAGASAGFPGLGDLH-----SSHEQQLQQQQY 889
            |......::....:.|.:.|...:.  .|| |:|:.....:|.....|     ||.........:
Zfish   127 GNITTQTSSSSGSMGGQSSDMEQVY--APPLPAYSTCGEIYPEQVTFHHSPATSSSLPYPSSDYH 189

  Fly   890 VRSQPKYQWLDSP-----ADYAQQQQQVQQVQQQQQQQQTL----VLPGPTSSASSSNAALGVLI 945
            ..|:|   .:|..     .||.....|......:.:..||:    |.|.|.:...:..|    ..
Zfish   190 TTSKP---GMDGSLFSMIPDYNLFHHQGDVGVMEHKPFQTMDPIRVNPPPITPLETIRA----FK 247

  Fly   946 PKQENYPDMQPSSNGTGYSGGSGGSSAAAAAAAAAAAAAVQLAEYSPSTSKGHEILSQVYQQSTV 1010
            .||:.:|         |:.|                               |.:.:||.:|.|..
Zfish   248 DKQQIHP---------GFLG-------------------------------GQQHVSQHHQPSQT 272

  Fly  1011 PLKLVPVKPRKYPNRPSKTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSF 1075
             |.|.|::|||||||||||||||||:|||.||||||||||||||||:|||||.||||||||||||
Zfish   273 -LALKPIRPRKYPNRPSKTPVHERPHACPAENCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSF 336

  Fly  1076 SRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKEKVRG 1128
            |||||||||||||||||||||:.||||||||||:||||||||||:.||...:|
Zfish   337 SRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQKDKKPTDKG 389

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
srNP_001262693.1 zf-C2H2 1036..1060 CDD:278523 20/23 (87%)
C2H2 Zn finger 1038..1060 CDD:275368 19/21 (90%)
zf-H2C2_2 1052..1077 CDD:290200 22/24 (92%)
C2H2 Zn finger 1068..1088 CDD:275368 19/19 (100%)
zf-H2C2_2 1080..1105 CDD:290200 22/24 (92%)
C2H2 Zn finger 1096..1116 CDD:275368 16/19 (84%)
egr3NP_001002647.1 DUF3446 88..158 CDD:288757 21/97 (22%)
C2H2 Zn finger 299..321 CDD:275368 19/21 (90%)
zf-H2C2_2 313..338 CDD:290200 22/24 (92%)
COG5048 325..>405 CDD:227381 56/65 (86%)
C2H2 Zn finger 329..349 CDD:275368 19/19 (100%)
zf-H2C2_2 341..366 CDD:290200 22/24 (92%)
C2H2 Zn finger 357..377 CDD:275368 16/19 (84%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 54 1.000 Domainoid score I11249
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000710
OrthoInspector 1 1.000 - - otm24421
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23235
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
ZFIN 00.000 Not matched by this tool.
77.090

Return to query results.
Submit another query.