Protein Alignment sr and Spps

DIOPT Version :10

• Sequence 1: NP_001262693.1
• Gene: sr / 42162
• FlyBaseID: FBgn0003499
• Length: 1271
• Species: Drosophila melanogaster
• Sequence 2: NP_001262902.1
• Gene: Spps / 42882
• FlyBaseID: FBgn0039169
• Length: 985
• Species: Drosophila melanogaster
• Alignment Length: 1004
• Identity: 228/1004 - (22%)
• Similarity: 336/1004 - (33%)
• Gaps: 325/1004 - (32%)

  Fly   274 PGTPSAAMIMEGLETLVAPTHHAFLLTETAAAAHFNVLSFDTCLFKTSTAAQSSGSPSTAT---- 334
            |.||.||   .|......|.:.|     :|||:.                .|..|:|.|.|
  Fly    16 PATPLAA---GGSSKATIPPNGA-----SAAASQ----------------TQVHGAPGTPTMQQI 56

  Fly   335 ---YLSPAQF-GGSHHGGASTSSNSLN--------SSSTASSSSTSSSLLHYTTASAAAAAAA-- 385
               :..|.|| ||:..|....:....|        ...|.:.....:..:....|..|.|.|.
  Fly    57 INIHQMPPQFAGGAVAGNGQNAGMPQNMFQIVQPMPMQTVNIDGQEAIFIPNLNAQLATAQAVNF 121

  Fly   386 ---AAAASANNSVLRARNQTATPTQGGSPGHVAVQPSATASSGRSSASHLSLLNTSGQHSPTSSA 447
               .|..:.|..:|||....|.|....     .:|.......|:.....:::..|:.| .|.::.
  Fly   122 NGQQAFITPNGQILRAPQMAANPAASN-----CIQLQQLNGLGQEQTQLITIPGTNIQ-IPVTNL 180

  Fly   448 VEQVEAHKQLIEA---------------------------LPGDLNTPVTTSSDIPSFFGPTTVV 485
            ::|.:..:|:.:.                           |||.:..|.|....      ||:|.
  Fly   181 IQQQQQAQQVHQGTVQQQAQGTNASGANGSGVTNSGTAGQLPGSITIPGTNLQI------PTSVA 239

  Fly   486 EPPPITGSI---------------ESEDLSLEPQVISVASPVLSHCSPLKEERSTPPALAIVKEE 535
            ....:.|:|               |:..|.:.||::...:|.:    |.:::     .:|:....
  Fly   240 AANGLLGNISNISNLLGGGQSIKLENGQLQMRPQLVQFPAPAM----PQQQQ-----TVAVQIPV 295

  Fly   536 SSNNSCNMYPQHNNNNNNNNNTTSSSTTTTSKQTTSESNTECVGSPGNHTQSHQQQQQQLQHNNT 600
            .:.|...:|                .|.....|..:.|:    |...|     ..|.|.||..:.
  Fly   296 QTANGQTIY----------------QTVHVPVQAAATSS----GGLQN-----LMQAQSLQMPSA 335

  Fly   601 SSSNSNCHHSHQQQ--QQQQQQQHMSSPQQQYQQHQILHQQQQLPNHHHHHHHHHHHHSQLQQLQ 663
            |          |.|  .|..|...:.:|..|.||.|:.....|||.:.:..|..:.|..|.||:|
  Fly   336 S----------QMQIIPQFSQIAQIVTPNGQIQQVQLAMPYPQLPPNANIIHIQNPHQQQQQQVQ 390

  Fly   664 QQQQQQQQQQQHQQQPLHQQQQLQHQQQQQHHQQHYQQHAIQHQQSQQQASKISYRG-------- 720
            |||||||.|||.|.    ||||.|.|||||..        .||||..|..|..|..|
  Fly   391 QQQQQQQAQQQQQA----QQQQAQQQQQQQVQ--------AQHQQLLQAISDASAGGQLPPNQPI 443

  Fly   721 -IFTTTGNAM---------NAAAAAAAAAAQQQHQQQQQHQQQLP---SPQLG---VLAGPMSPP 769
             |....|..:         ||..|...|.|......|..:.|.||   .|.||   ::.....||
  Fly   444 TITNAQGQQLTVIPAQLRPNAPTAPTPAPAGVPTPMQMPNLQALPIQNIPGLGQVQIIHANQLPP 508

  Fly   770 SNSLGNSWGLPSPDKTMFQPPLFSLPAHYATMQQQQQQQQQQQQQQQQQQAAGAAPSPYDDGRAA 834
            :        ||:    .||..|..||..:..:|.|.|.|...:|:.|         ||
  Fly   509 N--------LPA----NFQQVLTQLPMSHPQVQTQGQVQVMPKQEPQ---------SP------- 545

  Fly   835 AAAAAQHAELLGLTMDCTPLL--LKQPPPSYAG---ASAGFPGLGDLHSSHEQQLQQQQYVRSQP 894
                             |.::  :||.||...|   |:...|......::...|.||.:::.::.
  Fly   546 -----------------TQMITSIKQEPPDTFGPISATGNPPAPASTPNTASPQQQQIKFLHTES 593

  Fly   895 -KYQWLDSPADYAQQQQQVQQVQQQ----------------------------QQQQQTLVLP-- 928
             ....|..||..     |:..:.||                            ....|..:.|
  Fly   594 NSLSSLSIPASI-----QITALPQQATNTPNTPATTQPIPVSLPARSKVNAVTTSSTQITIAPTG 653

  Fly   929 -----------GPTSSASSSNAALGVLIPKQENYPDMQPS--SNGTGYSGGSGGSSAAAAAAAAA 980
                       |.|:|..|:|.:...:....:::.:|..|  |.|...:||.||::.........
  Fly   654 GQVVSVTTQARGATASIRSTNTSTTTITTPSQSHLNMNISVASVGGAATGGGGGTATGEPKPRLK 718

  Fly   981 AAAAVQLAEYSPSTSKGHEILSQVYQQSTVPLKLVPVKPRKYPNRPSKTPVHERPYACPVENCDR 1045
            ..|..     .|:.:.|                      .|:.::       :|.:.|.:..|.:
  Fly   719 RVACT-----CPNCTDG----------------------EKHSDK-------KRQHICHITGCHK 749

  Fly  1046 RFSRSDELTRHIRIHTGQKPFQC--RICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDE 1108
            .:.::..|..|:|.|||::||.|  ..|.:.|:|||.|..|.|||||||.|.|..|.:||.|||.
  Fly   750 VYGKTSHLRAHLRWHTGERPFVCSWAFCGKRFTRSDELQRHRRTHTGEKRFQCQECNKKFMRSDH 814

  Fly  1109 KKRHAKVHLKQR---------IKKEKVRG 1128
            ..:|.|.|.|.|         ||:|...|
  Fly   815 LSKHIKTHFKSRSGVELIELSIKQETKGG 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sr	NP_001262693.1	zf-C2H2	1036..1060	CDD:395048	5/23 (22%)
		C2H2 Zn finger	1038..1060	CDD:275368	5/21 (24%)
		zf-H2C2_2	1052..1077	CDD:463886	11/26 (42%)
		C2H2 Zn finger	1068..1088	CDD:275368	9/21 (43%)
		zf-H2C2_2	1080..1105	CDD:463886	14/24 (58%)
		C2H2 Zn finger	1096..1116	CDD:275368	9/19 (47%)
Spps	NP_001262902.1	SP1-4_N	<281..>371	CDD:425404	25/133 (19%)
		Atrophin-1	284..>630	CDD:460830	108/447 (24%)
		SP1-4_N	<713..741	CDD:425404	5/61 (8%)
		C2H2 Zn finger	742..764	CDD:275368	5/21 (24%)
		zf-H2C2_2	756..783	CDD:463886	11/26 (42%)
		C2H2 Zn finger	772..794	CDD:275368	9/21 (43%)
		zf-H2C2_2	786..809	CDD:463886	12/22 (55%)
		zf-C2H2	800..822	CDD:395048	10/21 (48%)
		C2H2 Zn finger	802..822	CDD:275368	9/19 (47%)