DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sr and hkb

DIOPT Version :9

Sequence 1:	NP_001262693.1	Gene:	sr / 42162	FlyBaseID:	FBgn0003499	Length:	1271	Species:	Drosophila melanogaster
Sequence 2:	NP_524221.1	Gene:	hkb / 40549	FlyBaseID:	FBgn0261434	Length:	297	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	96/318 - (30%)
Similarity:	136/318 - (42%)	Gaps:	82/318 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   827 PYDDGRAAAAAAAQHAELLGLTMDCTPLLLKQPPPS------YAGASAGFPGLGDLHSS------ 879
            |:|..|.||.:||             |..:||.|.:      .|.:|.|....||..|:
  Fly    18 PWDTQRQAATSAA-------------PRTVKQEPEAITIKTELASSSFGHDCDGDFSSASSSASS 69

  Fly   880 --------HEQQLQQQQYVR-SQPKYQWLDSPADYAQQQQQVQQVQQQQQQQQTLVLPGPTSSAS 935
                    :|:.|....|.| |.|.......|                       |...|.||..
  Fly    70 SSNSSKSCYEEALNHSSYTRTSTPLLDAAPHP-----------------------VFSHPQSSPL 111

  Fly   936 SSN-AALGVLIPKQENYPDMQPSSNGTGYSGGSGGSSAAAAAAAAAAAAAVQLAEYSPSTSKGHE 999
            .:: ||...|.|..::.|.:..:|: ..|      ::||||||||:...||......|.|.   .
  Fly   112 DTHAAATASLAPPNQHAPFLSAASD-LYY------AAAAAAAAAASTPTAVPGFGMDPFTM---G 166

  Fly  1000 ILSQVYQQ-STVPLKLVPVKPRKYPNRPSKTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQ 1063
            ::.|.|.: .....:|..:..||  .||.|       :.||  |||..||.:.:|..|||||||:
  Fly   167 LMEQEYARVMAEDAQLKALNSRK--QRPKK-------FKCP--NCDVAFSNNGQLKGHIRIHTGE 220

  Fly  1064 KPFQCRI--CMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQ 1119
            :||:|.:  |.::|:|::.||.|.|.|||.:|:.|..||:||.|.|..|:|.|.|:.|
  Fly   221 RPFKCDVNTCGKTFTRNEELTRHKRIHTGLRPYPCSACGKKFGRRDHLKKHMKTHMPQ 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sr	NP_001262693.1	zf-C2H2	1036..1060	CDD:278523	11/23 (48%)
		C2H2 Zn finger	1038..1060	CDD:275368	11/21 (52%)
		zf-H2C2_2	1052..1077	CDD:290200	13/26 (50%)
		C2H2 Zn finger	1068..1088	CDD:275368	8/21 (38%)
		zf-H2C2_2	1080..1105	CDD:290200	13/24 (54%)
		C2H2 Zn finger	1096..1116	CDD:275368	10/19 (53%)
hkb	NP_524221.1	COG5048	195..>261	CDD:227381	32/67 (48%)
		zf-C2H2	195..217	CDD:278523	11/23 (48%)
		C2H2 Zn finger	197..217	CDD:275368	11/21 (52%)
		zf-H2C2_2	210..236	CDD:290200	13/25 (52%)
		C2H2 Zn finger	225..247	CDD:275368	8/21 (38%)
		zf-H2C2_2	239..264	CDD:290200	13/24 (54%)
		C2H2 Zn finger	255..275	CDD:275368	10/19 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23235
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100