DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sr and Egr3

DIOPT Version :9

Sequence 1:	NP_001262693.1	Gene:	sr / 42162	FlyBaseID:	FBgn0003499	Length:	1271	Species:	Drosophila melanogaster
Sequence 2:	NP_058782.1	Gene:	Egr3 / 25148	RGDID:	2545	Length:	387	Species:	Rattus norvegicus

Alignment Length:	347	Identity:	135/347 - (38%)
Similarity:	176/347 - (50%)	Gaps:	85/347 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   838 AAQHAELLGLTMDCTPLLLKQPPP--SYAGASAGFPGLGDLHSSHEQQLQQQQYVRSQPKYQWLD 900
            |.::...:|||.:       :|.|  ||:|:....||              .:.|....|:.: |
  Rat    50 ATENVMDIGLTNE-------KPNPELSYSGSFQPAPG--------------NKTVTYLGKFAF-D 92

  Fly   901 SPADYAQQQQQVQQVQQQQQQQQTLVLPGPTSSASSSNAALGVLIPKQEN----YPDMQPSSN-G 960
            ||:::.|..      .........|.:|..:.:.|:......::.|.|.:    ||.:.|.|| |
  Rat    93 SPSNWCQDN------IISLMSAGILGVPPASGALSTQTTTASMVQPPQGDVEAMYPALPPYSNCG 151

  Fly   961 TGYS---------GGSGGSSAAAAAAAAAAAAAVQLAEYSPSTSKGH------------------ 998
            ..||         |..|.:.:.....:|..|....|....|..:..|
  Rat   152 DLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYNLYHHPNDMGSIPEHKPFQGMD 216

  Fly   999 ------------EILSQVYQQSTV----------PLKLVPVKPRKYPNRPSKTPVHERPYACPVE 1041
                        |.: :.::...:          ||.|.|::||||||||||||:||||:|||.|
  Rat   217 PIRVNPPPITPLETI-KAFKDKQIHPGFGSLPQPPLTLKPIRPRKYPNRPSKTPLHERPHACPAE 280

  Fly  1042 NCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARS 1106
            .||||||||||||||:|||||.|||||||||||||||||||||||||||||||:|:.||||||||
  Rat   281 GCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARS 345

  Fly  1107 DEKKRHAKVHLKQRIKKEKVRG 1128
            ||:|||||:||||:.||.:..|
  Rat   346 DERKRHAKIHLKQKEKKSEKGG 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sr	NP_001262693.1	zf-C2H2	1036..1060	CDD:278523	19/23 (83%)
		C2H2 Zn finger	1038..1060	CDD:275368	18/21 (86%)
		zf-H2C2_2	1052..1077	CDD:290200	22/24 (92%)
		C2H2 Zn finger	1068..1088	CDD:275368	19/19 (100%)
		zf-H2C2_2	1080..1105	CDD:290200	21/24 (88%)
		C2H2 Zn finger	1096..1116	CDD:275368	16/19 (84%)
Egr3	NP_058782.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	241..283		24/41 (59%)
		zf-C2H2	275..299	CDD:395048	19/23 (83%)
		C2H2 Zn finger	277..299	CDD:275368	18/21 (86%)
		COG5048	303..>375	CDD:227381	54/65 (83%)
		C2H2 Zn finger	307..327	CDD:275368	19/19 (100%)
		zf-H2C2_2	319..344	CDD:404364	21/24 (88%)
		C2H2 Zn finger	335..355	CDD:275368	16/19 (84%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	348..387		12/20 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I11026
eggNOG	1	0.900	-	-		E33208_3BH2K
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000710
OrthoInspector	1	1.000	-	-		otm45147
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.960