Protein Alignment sr and Egr2

DIOPT Version :9

• Sequence 1: NP_001262693.1
• Gene: sr / 42162
• FlyBaseID: FBgn0003499
• Length: 1271
• Species: Drosophila melanogaster
• Sequence 2: NP_001360912.1
• Gene: Egr2 / 13654
• MGIID: 95296
• Length: 483
• Species: Mus musculus
• Alignment Length: 370
• Identity: 150/370 - (40%)
• Similarity: 182/370 - (49%)
• Gaps: 70/370 - (18%)

  Fly   760 GVLAGPMSPPSNSLGNSWGLPSPDKTMFQPPLFSLPAHYATMQQQQQQQQQQQQQQQQQQAAGAA 824
            |:|.|...|.|.:..:|....||:      ||.:.|....||       .|.|.:.....:....
Mouse   132 GILQGVTPPASTTASSSVTSASPN------PLATGPLGVCTM-------SQTQPELDHLYSPPPP 183

  Fly   825 PSPYDDGRAAAAAAAQHAELLGLTMDCTPLLLKQPPPSYAGASAGF-PGL----GDLHSSHEQQL 884
            |.|| .|..........|.|...:...|..|..||||||....... |||    .|.........
Mouse   184 PPPY-SGCTGDLYQDPSAFLSPPSTTSTSSLAYQPPPSYPSPKPAMDPGLIPMIPDYPGFFPSPC 247

  Fly   885 QQQQYVRSQPKYQWLDSPADYAQQQQQVQQVQQQQQQQQTLVLPGPTSSASS-SNAALGVLIPKQ 948
            |:..:..:.|..:....|.|                   :|.:|.|.:..|: .|..||
Mouse   248 QRDPHGAAGPDRKPFPCPLD-------------------SLRVPPPLTPLSTIRNFTLG------ 287

  Fly   949 ENYPDMQPSSNGTGYSGGSGGSSAAAAAAAAAAAAAVQLAEYSPSTSKGHEILSQVYQQSTVPLK 1013
                  .|.:..|| .|.|||..  ......:.:|||....|:|     |.:          ||:
Mouse   288 ------GPGAGVTG-PGASGGGE--GPRLPGSGSAAVTATPYNP-----HHL----------PLR 328

  Fly  1014 LVPVKPRKYPNRPSKTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRS 1078
            .: ::||||||||||||||||||.||.|.||||||||||||||||||||.||||||||||:||||
Mouse   329 PI-LRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRS 392

  Fly  1079 DHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKK 1123
            ||||||||||||||||:||.||||||||||:|||.|:||:|:.:|
Mouse   393 DHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERK 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sr	NP_001262693.1	zf-C2H2	1036..1060	CDD:278523	20/23 (87%)
		C2H2 Zn finger	1038..1060	CDD:275368	19/21 (90%)
		zf-H2C2_2	1052..1077	CDD:290200	22/24 (92%)
		C2H2 Zn finger	1068..1088	CDD:275368	18/19 (95%)
		zf-H2C2_2	1080..1105	CDD:290200	22/24 (92%)
		C2H2 Zn finger	1096..1116	CDD:275368	16/19 (84%)
Egr2	NP_001360912.1	DUF3446	107..179	CDD:371803	15/59 (25%)
		zf-C2H2	350..374	CDD:333835	20/23 (87%)
		C2H2 Zn finger	352..374	CDD:275368	19/21 (90%)
		COG5048	378..>434	CDD:227381	48/55 (87%)
		C2H2 Zn finger	382..402	CDD:275368	18/19 (95%)
		C2H2 Zn finger	410..430	CDD:275368	16/19 (84%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11592
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2858
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000710
OrthoInspector	1	1.000	-	-		otm43081
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	6.010