Protein Alignment sr and sr

DIOPT Version :10

• Sequence 1: NP_001262693.1
• Gene: sr / 42162
• FlyBaseID: FBgn0003499
• Length: 1271
• Species: Drosophila melanogaster
• Sequence 2: XP_061498906.1
• Gene: sr / 1273196
• VectorBaseID: AGAMI1_000792
• Length: 1148
• Species: Anopheles gambiae
• Alignment Length: 1391
• Identity: 551/1391 - (39%)
• Similarity: 653/1391 - (46%)
• Gaps: 442/1391 - (31%)

  Fly     2 LLTMRRQNELIVGSQQHPSATSSASS------------SAGATSSPGLSGQNLNLVAGAGAATNS 54
            :|.|||::|.|.||   .|||::.::            ...|..||  |||       :|..||.
Mosquito     1 MLAMRRESEPIYGS---ASATTNYNNLLHHHGQHHNGHHLQAVQSP--SGQ-------SGHPTNG 53

  Fly    55 TSANSQDSLNTPTTPLLGLSRNPLQFAPPPAPPIAVPNPAASGPTFGYYQTVN------------ 107
            |:|......:......||.:                 :|...|...|::|..:
Mosquito    54 TAAEPSVRAHPAENGTLGET-----------------DPGGLGAFQGHHQQQHQQHQQQQLLQQQ 101

  Fly   108 ---------AAPPIHH-------SPAAT----------------------------SEVSTAPQP 128
                     .:...||       |||.|                            |..||.|..
Mosquito   102 QQLADHQQTLSHQHHHHSHRSALSPATTVSFGGLPGLCNGSSSYAGYTSFGLNSSSSGRSTHPAA 166

  Fly   129 PVELDEYVDILQVQQLLLDSSA-------------------------AAAAAANNPPTTEQSVQQ 168
            . .|||||||||||||||::|:                         .::::::||.::..|...
Mosquito   167 S-SLDEYVDILQVQQLLLENSSTPSGSTSSSTVASITTASGTSTTTTTSSSSSSNPSSSSSSSTS 230

  Fly   169 PQQNTVVQPHPHQQQQQQQQQQ-----QPQQQQQQPQQIL-AKPRPRINLQKATEYAAQLA---- 223
            ....|:    |....|......     .|..........| ||.||::|||||.:::|..|
Mosquito   231 TSSTTI----PSTASQHIPPVSTVPFFAPSSAPSTSTAALHAKNRPKVNLQKAADFSAAAAAAAA 291

  Fly   224 ------QAESSSPGSRRVLLDYPSPYLYGNPYHHHTPPGEDLVALWFGSNGTGGVAPGTPSAAMI 282
                  |.:..|| |:|:|.||||||||||   :|..|.:||||||||||||||||||.|:||||
Mosquito   292 AAAAANQLQGDSP-SKRLLFDYPSPYLYGN---YHPSPSDDLVALWFGSNGTGGVAPGPPAAAMI 352

  Fly   283 MEGLETLVAPTHHAFLLTETAAAAHFNVLSFDTC-LFKTSTAAQSSG------------------ 328
            ||||||||||:||.|||||:|||||||||||||| ||||.|...|.|
Mosquito   353 MEGLETLVAPSHHTFLLTESAAAAHFNVLSFDTCGLFKTGTTTTSLGLNNNSTTTPNNNHHHHLY 417

  Fly   329 -------SPSTATYLSPAQFGGSHHGGASTSSNSL----------NSSSTASSSSTSSSLLHYTT 376
                   :.||||.|:..|....||...||:.:..          :|:||..|||..||.:
Mosquito   418 HPYHHQTAVSTATALAHHQPHHHHHQHHSTTQHQQQQQQQQHQHNSSASTIVSSSAVSSAI---- 478

  Fly   377 ASAAAAAAAAAAASANNSVLRARNQTATPTQGGSPGHVAVQPSATASSGRSSASHLSLLNTSG-- 439
            ||||::.|.....:|..||..|.:.        |.||         |....:..|||||:|.|
Mosquito   479 ASAASSTAITTHTTATTSVTAASHT--------SHGH---------SHHHPNHPHLSLLSTGGGG 526

  Fly   440 ---QHSPTSSAVEQ--VEAHKQ-LIEALPGDLNTPVTTSSDIPSFFGPTTVVEPPPITGSIESED 498
               .||..||.:..  .:.|.| ..:|..||||||||||.||||||||:||||||||||||||:|
Mosquito   527 STSHHSNDSSTLHSGTGDDHSQSQTDAQAGDLNTPVTTSGDIPSFFGPSTVVEPPPITGSIESDD 591

  Fly   499 LSLEPQVISVASPVLSHCSPLKEERSTPPALAIVKEESSNNSCNMYPQHNNNNNNNNNTTSSSTT 563
            ||||||.:|  ||.:|.|||.|:|||||.  :||.||.:
Mosquito   592 LSLEPQTVS--SPCVSLCSPTKQERSTPQ--SIVNEEEA-------------------------- 626

  Fly   564 TTSKQTTSESNTECVGSPGNHTQSHQQQQQQLQHNNTSSSNSNCHHSHQQQQQQQQQQHMSSPQQ 628
                                              :||||:|:....|..||||||
Mosquito   627 ----------------------------------SNTSSTNTMYPSSGAQQQQQQ---------- 647

  Fly   629 QYQQHQILHQQQQLPNHHHHHHHHHHHHSQLQQLQQQQQQQQQQQQHQQQPLHQQQQLQHQQQQQ 693
                                              |||||||||||||.   ||.|.::.......
Mosquito   648 ----------------------------------QQQQQQQQQQQQHS---LHGQIRVAGLASVT 675

  Fly   694 --HHQQHYQQHAIQHQQSQQQASKISYRGIFTTTGNAMNAAAAAAAAAAQQQHQQQQQHQQQLPS 756
              ...||.....:  |.|....:||:||||||::|                             |
Mosquito   676 GGADMQHGSNDGV--QSSDAIENKIAYRGIFTSSG-----------------------------S 709

  Fly   757 PQLGVL-------AGPMSPPSNSLGNSWGLPSPDKTMFQPPLFSLPAHYATMQQQQQQQQQQQQQ 814
            |.:|:.       ||.|||.: .|| .|||||||||:||.|:|.|....||...|..........
Mosquito   710 PSMGLQAGNVMAGAGQMSPTA-GLG-GWGLPSPDKTLFQAPMFGLLGPQATSASQGVSATSPSIG 772

  Fly   815 QQQQQAAGAAPSPYDDGRAAAAAAAQH-AELLGLTMDCTPLLLKQPPPSYAGA------------ 866
            |..|...|..    :.|...|.....| ||||||.|||..::||| ||||:..
Mosquito   773 QHHQHHYGGD----ERGHTGAGHGGGHGAELLGLNMDCASIILKQ-PPSYSSCVGSLDMQQGQDM 832

  Fly   867 -SAGFPGLGDLHSSHEQQLQQQQYVRSQPKYQWLDSPAD-YAQQQQQVQQVQQQQQQQQTLVLPG 929
             ..|.||.|   :...||:.|        ||||||||.| |.           ...|..::||||
Mosquito   833 HGYGRPGQG---AGLGQQMSQ--------KYQWLDSPVDPYV-----------GSPQHGSVVLPG 875

  Fly   930 PTSSASSSNAALGVLIPKQENYPDMQPSSNGTGYSGGSGGSSAAAAAAAAAAAAAVQLAEYSPST 994
            |    ||:..::|.:|||||.|......::.:...||     ...|.||..|..|||||||:.:|
Mosquito   876 P----SSTPISVGPIIPKQEPYSTPNACTSDSSQLGG-----LTPAQAAQQAQYAVQLAEYNQAT 931

  Fly   995 SKGHEILSQVYQQSTVPLKLVPVKPRKYPNRPSKTPVHERPYACPVENCDRRFSRSDELTRHIRI 1059
            |||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   932 SKGHEILSQVYQQSTMPLKLVPVKPRKYPNRPSKTPVHERPYACPVENCDRRFSRSDELTRHIRI 996

  Fly  1060 HTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKE 1124
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   997 HTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKKE 1061

  Fly  1125 K--------------VRGEQQQQQQQQQQQQQQQQQQQLQQQQEQHHLSLQQHQQY---QQHHLL 1172
            |              ...........|||||||||||...|||:|||..|..|..:   ..||||
Mosquito  1062 KNSSSGGNSANSNNSSASAAHHTHHAQQQQQQQQQQQHHHQQQQQHHQQLGHHPGHPGLHAHHLL 1126

  Fly  1173 HSADLA---IVTSSASMXRLENSASS 1195
            ...||.   ||:||:      |.|:|
Mosquito  1127 THDDLTGIPIVSSSS------NPANS 1146

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sr	NP_001262693.1	zf-C2H2	1036..1060	CDD:395048	23/23 (100%)
		C2H2 Zn finger	1038..1060	CDD:275368	21/21 (100%)
		zf-H2C2_2	1052..1077	CDD:463886	24/24 (100%)
		C2H2 Zn finger	1068..1088	CDD:275368	19/19 (100%)
		zf-H2C2_2	1080..1105	CDD:463886	24/24 (100%)
		C2H2 Zn finger	1096..1116	CDD:275368	19/19 (100%)
sr	XP_061498906.1	None