DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sr and klf15

DIOPT Version :9

Sequence 1:	NP_001262693.1	Gene:	sr / 42162	FlyBaseID:	FBgn0003499	Length:	1271	Species:	Drosophila melanogaster
Sequence 2:	XP_002938279.1	Gene:	klf15 / 100495857	XenbaseID:	XB-GENE-854149	Length:	394	Species:	Xenopus tropicalis

Alignment Length:	414	Identity:	88/414 - (21%)
Similarity:	141/414 - (34%)	Gaps:	113/414 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   752 QQLPSPQLGVLAGPMSPPSNSLGNSWGLPSPDKTMFQPPLFSLPAHYATMQQQQQQQQQQQQQQQ 816
            |.|||        |.|...:...:.....|||..:       |.:.|.:....:.|.........
Frog    32 QMLPS--------PTSEDDSDSSSFRSCSSPDSQV-------LSSSYGSACSAESQDNILDYLLS 81

  Fly   817 QQQAAGAAPSPYDDGRAAAAAAAQHAEL--LGLTMDCTPLLLKQPPPSYAGASAGFPGLGDLHSS 879
            |.....|:.|.:|..|.......:..::  .|:.|:.|...              .|.|.::
Frog    82 QTSLGNASLSWWDKRRQQPVVKEEFLKVPEFGVDMEETTFF--------------HPTLDEI--- 129

  Fly   880 HEQQLQQQQYVRSQPKYQWLDSPADYAQQQQQVQQVQQQQQQQQTLVLPGPTSSASSS--NAALG 942
                   ::::....|..:.|.....|::.:...|:...         |...:|:...  |....
Frog   130 -------EEFLEENMKTDFKDEDRHDAKELRTCGQLFSD---------PHAVNSSMKEDINGETI 178

  Fly   943 VLIPKQENYPDMQPSSNGTGYSGGSGGSSAAAAAAAAAAAAAVQLAEYS-----------PSTSK 996
            :.:|:.||                :.||.|.:..........:|..|..           |...|
Frog   179 LSVPEDEN----------------TKGSDAVSVEGGIPVILQIQPIEIKQESNTNQSSQFPENIK 227

  Fly   997 GHEIL-----------SQVYQQSTVPLKLVPVKPRKYPNRP-------------------SKTPV 1031
            ..::|           .|:.|.|.:..|.|.:.|.....:|                   .|.|.
Frog   228 VAQLLVNIQGQTFALVPQLVQSSNLSSKFVRIAPVPIAAKPVGPGGGIQGQAGVMIGQKFQKNPA 292

  Fly  1032 HE--RPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRI--CMRSFSRSDHLTTHIRTHTGEK 1092
            .|  :.:.|....|.:.:::|..|..|:|.|||:|||.|..  |...|||||.|:.|.|:|:|.|
Frog   293 TELIKMHKCTFPGCTKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVK 357

  Fly  1093 PFSCDICGRKFARSDEKKRHAKVH 1116
            |:.|.:|.:||||||...:|.|||
Frog   358 PYQCAVCEKKFARSDHLSKHIKVH 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sr	NP_001262693.1	zf-C2H2	1036..1060	CDD:278523	6/23 (26%)
		C2H2 Zn finger	1038..1060	CDD:275368	6/21 (29%)
		zf-H2C2_2	1052..1077	CDD:290200	12/26 (46%)
		C2H2 Zn finger	1068..1088	CDD:275368	10/21 (48%)
		zf-H2C2_2	1080..1105	CDD:290200	11/24 (46%)
		C2H2 Zn finger	1096..1116	CDD:275368	10/19 (53%)
klf15	XP_002938279.1	SFP1	<284..379	CDD:227516	38/94 (40%)
		C2H2 Zn finger	301..323	CDD:275368	6/21 (29%)
		C2H2 Zn finger	331..353	CDD:275368	10/21 (48%)
		zf-H2C2_2	345..370	CDD:372612	11/24 (46%)
		C2H2 Zn finger	361..381	CDD:275368	10/19 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940