DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sr and osr2

DIOPT Version :9

Sequence 1:	NP_001262693.1	Gene:	sr / 42162	FlyBaseID:	FBgn0003499	Length:	1271	Species:	Drosophila melanogaster
Sequence 2:	XP_002934454.1	Gene:	osr2 / 100038196	XenbaseID:	XB-GENE-481907	Length:	312	Species:	Xenopus tropicalis

Alignment Length:	329	Identity:	83/329 - (25%)
Similarity:	125/329 - (37%)	Gaps:	104/329 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   867 SAGFPGLGDLHSSHEQQLQQQQYVRSQPKYQWLDSPA--DYAQQQQQVQQVQQQQQQQQTLVLP- 928
            |...|....||.|  .||....::::...:     ||  |:.|....:..||.......||..|
Frog     3 SKALPAPIPLHPS--LQLTNYSFLQAVNTF-----PAAVDHLQGLYGLSAVQTMHMNHWTLGYPN 60

  Fly   929 --GPTSSASSSNAALGVLIPKQENYPDMQPSSNGTGYSGGSGGSSAAAAAA----------AAAA 981
              |.|.|..:..||...|:..:.::|.: |.:  |.......|:.|....|          |..|
Frog    61 MHGITRSTITEMAAAQGLMDARFSFPAL-PFA--THLFHPKQGAIAHVIPALHKDRPRFDFANLA 122

  Fly   982 AAAVQ--------LAEYSPSTSKGHEILSQVYQQSTVPLKLVPVKPRKYPNR---PSKTP----- 1030
            .||.|        |::.||.....   :|::.:.|          |.:.|:|   ||||.
Frog   123 IAATQEDPPKIGDLSKLSPGLGSP---ISEISKLS----------PDRKPSRGRLPSKTKKEFIC 174

  Fly  1031 --------------VH------ERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCR------ 1069
                          :|      ||||.|.:  |.:.|.|.|.|..|..||:.:|||:|:
Frog   175 KFCGRHFTKSYNLLIHERTHTDERPYTCDI--CHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGF 237

  Fly  1070 ----------------------ICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRH 1112
                                  .|.|:|::..:|.||:.|||..||:||:.||:.|.|:.:.:||
Frog   238 CQSRTLAVHKTLHMQESPHKCPTCGRTFNQRSNLKTHLLTHTDIKPYSCEQCGKVFRRNCDLRRH 302

  Fly  1113 AKVH 1116
            :..|
Frog   303 SLTH 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sr	NP_001262693.1	zf-C2H2	1036..1060	CDD:278523	8/23 (35%)
		C2H2 Zn finger	1038..1060	CDD:275368	7/21 (33%)
		zf-H2C2_2	1052..1077	CDD:290200	11/52 (21%)
		C2H2 Zn finger	1068..1088	CDD:275368	7/47 (15%)
		zf-H2C2_2	1080..1105	CDD:290200	13/24 (54%)
		C2H2 Zn finger	1096..1116	CDD:275368	7/19 (37%)
osr2	XP_002934454.1	C2H2 Zn finger	174..194	CDD:275368	1/19 (5%)
		zf-H2C2_2	186..211	CDD:372612	8/26 (31%)
		C2H2 Zn finger	202..222	CDD:275368	7/21 (33%)
		zf-H2C2_2	214..237	CDD:372612	8/22 (36%)
		C2H2 Zn finger	230..250	CDD:275368	1/19 (5%)
		COG5048	251..>312	CDD:227381	20/56 (36%)
		C2H2 Zn finger	258..278	CDD:275368	6/19 (32%)
		C2H2 Zn finger	286..306	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030