| Sequence 1: | NP_524394.2 | Gene: | htl / 42160 | FlyBaseID: | FBgn0010389 | Length: | 729 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_047275401.1 | Gene: | RIPK1 / 8737 | HGNCID: | 10019 | Length: | 712 | Species: | Homo sapiens |
| Alignment Length: | 376 | Identity: | 101/376 - (26%) |
|---|---|---|---|
| Similarity: | 159/376 - (42%) | Gaps: | 67/376 - (17%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 387 TVLQNGNEPAPFNEY-EFPLDSNWEL-----PRSHLVLGATLGEGAFGRVVMA-EVNNAIVAVKM 444
Fly 445 VKEG-----HTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYK 504
Fly 505 NRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYV 569
Fly 570 LKIADFGLA-------------RDIQSTDYYRKNTNGRLPIKWMAPESLQE--KFYDSKSDVWSY 619
Fly 620 GILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEK---PAKCSMNIYILMRQCWHFNADDRPPF 681
Fly 682 TEIVE-----YMDKLLQTKEDYLDVDIANLDTPPSTSDEEEDETDNLQKWC 727 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| htl | NP_524394.2 | Ig | 101..191 | CDD:472250 | |
| Ig strand B | 121..125 | CDD:409353 | |||
| Ig strand C | 134..138 | CDD:409353 | |||
| Ig strand E | 157..161 | CDD:409353 | |||
| Ig strand F | 171..176 | CDD:409353 | |||
| Ig strand G | 184..187 | CDD:409353 | |||
| Ig | 200..289 | CDD:472250 | |||
| Ig strand B | 216..220 | CDD:409353 | |||
| Ig strand C | 229..233 | CDD:409353 | |||
| Ig strand E | 255..259 | CDD:409353 | |||
| Ig strand F | 269..274 | CDD:409353 | |||
| Ig strand G | 282..285 | CDD:409353 | |||
| Protein Kinases, catalytic domain | 404..692 | CDD:473864 | 87/321 (27%) | ||
| RIPK1 | XP_047275401.1 | STKc_RIP1 | 64..331 | CDD:270929 | 83/294 (28%) |
| Death_RIP1 | 624..709 | CDD:260048 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||