DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment htl and AT1G29730

DIOPT Version :9

Sequence 1:	NP_524394.2	Gene:	htl / 42160	FlyBaseID:	FBgn0010389	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001322634.1	Gene:	AT1G29730 / 839851	AraportID:	AT1G29730	Length:	1001	Species:	Arabidopsis thaliana

Alignment Length:	759	Identity:	165/759 - (21%)
Similarity:	263/759 - (34%)	Gaps:	236/759 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 TRPSGSLLTLNCHALGNPEPNITWYRNG--TVDWTRGYGSLKRNRWTLTMEDLVPGDCGNYTCKV 176
            |..|...|.|....|..|.|...|....  |:|       |..||  ||.|.........||...
plant   287 TSTSLKYLVLRNINLSGPIPTSIWDLPSLMTLD-------LSFNR--LTGEIPAYATAPKYTYLA 342

  Fly   177 CNSLGCIRHDTQVIVSDRVNHKPILMTGPLNLTLVVNS-TGSMHCK-------YLSDLTSKKAWI 233
            .|.|           |.:|.....| |...|:.|..|: |.|..||       |.|..:..:...
plant   343 GNML-----------SGKVETGAFL-TASTNIDLSYNNFTWSPMCKERKNINTYESSHSKNRLTR 395

  Fly   234 FVPCHGMTNCSN-NRSI----------IAEDKDQL---------------------------DFV 260
            .:||..:..|.| :||:          |...:.:.                           ||:
plant   396 LLPCSAIKQCQNYSRSLHINCGGPDVTIENSRGRFLYEGDNYGLTGSATNYYRKNWGYSNTGDFM 460

  Fly   261 NVRMEQEGWYTCVESNSLGQSNSTAYLRVVRS-------LHVLEAGVASGSLHSTSFVY------ 312
            :..: .|..||....:::.......|....||       ....|.|..:..||.....:
plant   461 DDAI-TEDTYTVSSESAVSAKYPDLYQNARRSPLSLAYYAFCFENGSYNVKLHFAEIQFSDVEPY 524

  Fly   313 ---------IFVFGGLIFIFMTTLFVFYAIRKM---KHEKVLKQRIETVHQWTKKVIIFKPEGGG 365
                     |::.|.||       :..::||:.   .|::|:::...||...|.::.::....|
plant   525 TKLAKRVFNIYIQGKLI-------WEDFSIREEANGTHKEVIREVNTTVTDNTLEIRLYWAGKG- 581

  Fly   366 DSSGSMDTMIMPVVRIQKQRTTVLQNGNEPAPFNEYE-------FPLDSNWELPRSHLVLGATL- 422
                   |||:|    |:.....|.:.....|.:|.|       .|:..:.:..:..|:||.||
plant   582 -------TMIIP----QRGYYGSLISAVSVCPSSESECGVPVQFLPVKKDHKPTKYPLILGLTLS 635

  Fly   423 --------------------------------------------GEGAFGRVVMAEV-NNAIVAV 442
                                                        |||.||.|....: :..::||
plant   636 LAFLLLAAFCWRKCVSNANAAERGSFSLRQLKVATNDFDPLNKIGEGGFGSVYKGRLPDGTLIAV 700

  Fly   443 -KMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNR 506
             |:..:.|..:  ...|.|:.::..: :|.|::.|.|||.:...|.::.||..:..|.|.|
plant   701 KKLSSKSHQGN--KEFVNEIGMIACL-QHPNLVKLYGCCVEKNQLLLVYEYLENNCLSDAL---- 758

  Fly   507 PFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYL---ASRRCIHRDLAARNVLVSDDY 568
             |||     |.........|        |....||||:.:|   ::.:.||||:...|||:..|.
plant   759 -FGR-----SCLKLEWGTRH--------KICLGIARGLAFLHEDSAVKIIHRDIKGTNVLLDKDL 809

  Fly   569 VLKIADFGLAR---DIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMT-- 628
            ..||:||||||   |.||    ...|.....|.:||||.........|:||:|:|::..||::
plant   810 NSKISDFGLARLHEDNQS----HITTRVAGTIGYMAPEYAMRGHLTEKADVYSFGVVAMEIVSGK 870

  Fly   629 ------------YGQQPYPTIMS-----AEELYTYL------MSGQRMEKPAKCSMNIYILMRQC 670
                        .|...:..::.     ||.|...|      |..:||.|       :.:|   |
plant   871 SNAKYTPDDECCVGLLDWAFVLQKKGDIAEILDPRLEGMFDVMEAERMIK-------VSLL---C 925

  Fly   671 WHFNADDRPPFTEIVEYMDKLLQTKEDYLDVDI--ANLDTPPST 712
            .:.::..||..:::|:.::...:.::...|..:  .||...||:
plant   926 ANKSSTLRPNMSQVVKMLEGETEIEQIISDPGVYSDNLHFKPSS 969

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
htl	NP_524394.2	Ig	112..191	CDD:299845	20/78 (26%)
		IG_like	113..191	CDD:214653	20/78 (26%)
		IG_like	205..289	CDD:214653	22/129 (17%)
		PKc_like	404..692	CDD:304357	87/365 (24%)
		STYKc	416..688	CDD:214568	86/349 (25%)
AT1G29730	NP_001322634.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I2197
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050