DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment htl and AT2G39360

DIOPT Version :9

Sequence 1:	NP_524394.2	Gene:	htl / 42160	FlyBaseID:	FBgn0010389	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_181468.1	Gene:	AT2G39360 / 818521	AraportID:	AT2G39360	Length:	815	Species:	Arabidopsis thaliana

Alignment Length:	697	Identity:	151/697 - (21%)
Similarity:	265/697 - (38%)	Gaps:	193/697 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 NKADLPVNVSSKPYWRNPKKMSFLQTR---PSGSLLTLNCHALGNPEPNITWYRNGTVDWTRGYG 150
            |..:|.|:......||.....|..:..   |..:|..:|..|.|..:.....|..||.  ||...
plant   206 NMGNLSVSRDQDKLWRQWDSDSAYKAHFGTPVMNLKAVNFSAGGITDDIAPVYVYGTA--TRLNS 268

  Fly   151 SLKRN-----RWTLTMEDLVPGDCGNYTCKVCNSL-------GCIRHDTQVIVSDRVNHKPILMT 203
            .|..|     .||..:|   ||.........||.:       ..||.|. .:.|::|.
plant   269 DLDPNTNANLTWTFKVE---PGFDYFVRFHFCNIIVDPFGFERQIRFDI-FVNSEKVR------- 322

  Fly   204 GPLNLTLVVNSTGSMHCKYLSDLTSKKAWIFVPCHGMTNCS---------------NNRSI--IA 251
             .:::|.|:|  |:....:..|...:||   ....|..|.|               |...|  ::
plant   323 -TIDMTEVLN--GTFGAPFFVDAVMRKA---KSREGFLNLSIGLVMDVSSYPVSFINGFEISKLS 381

  Fly   252 EDKDQLDFVNVRMEQEGWYTCVESNSLGQSNSTAYLRVVRSLHVLEAGVASGSLHSTSFVYIFVF 316
            .||..||..:..:.        :.:|..:|::|:            .|:.:|.  |.:.....||
plant   382 NDKRSLDAFDAILP--------DGSSSNKSSNTS------------VGLIAGL--SAALCVALVF 424

  Fly   317 GGLIFIFMTTLFVFYAIRKMKHEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGSMDTMIMPVVRI 381
            |.::        .::.|||.:..   .::::|||            ..||..           :|
plant   425 GVVV--------SWWCIRKRRRR---NRQMQTVH------------SRGDDH-----------QI 455

  Fly   382 QKQRTTVLQNGNEPAPFNE----YEFPLDSNWELPRSHLVLGAT--------LGEGAFGRVVMAE 434
            :|..|      .|...|:.    |.:||         .|:..||        :|.|.||:|....
plant   456 KKNET------GESLIFSSSKIGYRYPL---------ALIKEATDDFDESLVIGVGGFGKVYKGV 505

  Fly   435 VNNAI-VAVK----MVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAP 494
            :.:.. ||||    ..::|     :|....|:|::... ||.::::|:|.|.:|..:.::.||..
plant   506 LRDKTEVAVKRGAPQSRQG-----LAEFKTEVEMLTQF-RHRHLVSLIGYCDENSEMIIVYEYME 564

  Fly   495 HGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYL---ASRRCIHRD 556
            .|.|||.||           |....|.      ::.:..::.....|||:.||   ::|..||||
plant   565 KGTLKDHLY-----------DLDDKPR------LSWRQRLEICVGAARGLHYLHTGSTRAIIHRD 612

  Fly   557 LAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGI 621
            :.:.|:|:.|:::.|:|||||::.....|....:|..:....::.||.|..:....||||:|:|:
plant   613 VKSANILLDDNFMAKVADFGLSKTGPDLDQTHVSTAVKGSFGYLDPEYLTRQQLTEKSDVYSFGV 677

  Fly   622 LLWEIMTYGQQPYPTIMSAEE-------------------LYTYLMSGQRMEKPAK-CSMNIYIL 666
            ::.|::. |:......:..|:                   :..:|:...::|:..| |.:.
plant   678 VMLEVVC-GRPVIDPSLPREKVNLIEWAMKLVKKGKLEDIIDPFLVGKVKLEEVKKYCEVT---- 737

  Fly   667 MRQCWHFNADDRPPFTEIVEYMDKLLQTKEDYLDVDIANLDTPPSTS 713
             .:|...|..:||...:::..::.:||.:..  |...|.:|..|..|
plant   738 -EKCLSQNGIERPAMGDLLWNLEFMLQVQAK--DEKAAMVDDKPEAS 781

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
htl	NP_524394.2	Ig	112..191	CDD:299845	22/93 (24%)
		IG_like	113..191	CDD:214653	22/92 (24%)
		IG_like	205..289	CDD:214653	19/100 (19%)
		PKc_like	404..692	CDD:304357	75/323 (23%)
		STYKc	416..688	CDD:214568	73/307 (24%)
AT2G39360	NP_181468.1	Malectin_like	33..379	CDD:372329	42/191 (22%)
AT2G39360	NP_181468.1	STKc_IRAK	493..759	CDD:270968	70/294 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I2197
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050