| Sequence 1: | NP_524394.2 | Gene: | htl / 42160 | FlyBaseID: | FBgn0010389 | Length: | 729 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000450.3 | Gene: | TEK / 7010 | HGNCID: | 11724 | Length: | 1124 | Species: | Homo sapiens |
| Alignment Length: | 716 | Identity: | 205/716 - (28%) |
|---|---|---|---|
| Similarity: | 314/716 - (43%) | Gaps: | 178/716 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 95 VNVSSKPYWRN-PKKMSFLQTRP------------SGSLLTLN----------CHAL-------- 128
Fly 129 GNPEPNITWYRNGTVDW--TRGYGSLKRNRWT--LTMEDLVPGD--------------------- 168
Fly 169 --CGNYTCKVCNSLGCIRHD-TQVIVSDRVNHK---------------PILMTGPLNLTLVVNST 215
Fly 216 GSMHCKYLSDLTSKKA---WIFVPCHGMTNCSNNRSIIAEDKDQLDFVNVR-----------MEQ 266
Fly 267 EGWY--TCVESNSLGQSNSTAYLRVVRSLHVLEAGVASGSLHSTSFVYIFVFGGLIFIFMTTLFV 329
Fly 330 FYAIRKMKHEKV---LKQRIETVHQWTKKVIIFKPEGGGDSSGSM----------DTMIMPVVRI 381
Fly 382 QKQRTTVLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAEVN----NAIVAV 442
Fly 443 KMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRP 507
Fly 508 FGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKI 572
Fly 573 ADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTI 637
Fly 638 MSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKEDYLDVD 702
Fly 703 I 703 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| htl | NP_524394.2 | Ig | 112..191 | CDD:299845 | 24/136 (18%) |
| IG_like | 113..191 | CDD:214653 | 23/135 (17%) | ||
| IG_like | 205..289 | CDD:214653 | 16/99 (16%) | ||
| PKc_like | 404..692 | CDD:304357 | 126/291 (43%) | ||
| STYKc | 416..688 | CDD:214568 | 126/275 (46%) | ||
| TEK | NP_000450.3 | Ig_Tie2_1 | 24..118 | CDD:402176 | |
| EGF_Lam | 230..275 | CDD:238012 | |||
| EGF_Lam | 314..>342 | CDD:238012 | |||
| IgI_Tie2 | 348..439 | CDD:409556 | |||
| Ig strand B | 366..370 | CDD:409556 | |||
| Ig strand C | 382..386 | CDD:409556 | |||
| Ig strand E | 407..411 | CDD:409556 | |||
| Ig strand F | 421..426 | CDD:409556 | |||
| Ig strand G | 434..437 | CDD:409556 | |||
| fn3 | 445..520 | CDD:394996 | 13/56 (23%) | ||
| fn3 | 544..626 | CDD:394996 | 19/85 (22%) | ||
| FN3 | 639..731 | CDD:238020 | 17/108 (16%) | ||
| PTKc_Tie2 | 816..1118 | CDD:133219 | 132/332 (40%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||