DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment htl and si:ch211-167j9.5

DIOPT Version :9

Sequence 1:	NP_524394.2	Gene:	htl / 42160	FlyBaseID:	FBgn0010389	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	XP_693602.5	Gene:	si:ch211-167j9.5 / 565221	ZFINID:	ZDB-GENE-131121-210	Length:	400	Species:	Danio rerio

Alignment Length:	425	Identity:	111/425 - (26%)
Similarity:	198/425 - (46%)	Gaps:	62/425 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 GSLHSTSFVYIFVFGGLIFIFMTTL--FVFYAIRKMKHEKVLKQRIETVHQWTKKVIIFKPEGGG 365
            |.:....|:.:....|:...||..|  ..|:..|.      ||:.|..:.|....||   |....
Zfish     2 GDIKDPGFIILISVYGVTVFFMAVLGFLCFHKYRS------LKKTIRDLKQGRPTVI---PRAAS 57

  Fly   366 DSSG--SMDTMIMPVV-------RIQKQRTTVLQNGNEPAPFNEYEFPLDSNWELPR-----SHL 416
            ..|.  |.:.:.:|..       .:|:|:|.           :..:||..::.::||     .:|
Zfish    58 HDSSPPSPNVLTLPEAPEPIAESPLQRQQTK-----------SSCKFPWKTSQQVPRFTKEDLNL 111

  Fly   417 VLGATLG-EGAF--GRVVMAEV-NNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLL 477
            :.....| ||.|  .|::.... .::::..|:.|||.|.   ..:..|..:|:.:..|.|::.||
Zfish   112 IQLIKAGREGVFYKARIIRGTCRGHSLITCKIGKEGMTS---KQMEHEASIMRKLAYHKNVMQLL 173

  Fly   478 GCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIAR 542
            ...:...|..:|:|:..:|.|:.|:.|::      |..|:.|.        .::.....::.||.
Zfish   174 DWNTAEEPYLLIMEFMSYGTLRTFVQKHK------DELSADPE--------LQRHFTIASYHIAM 224

  Fly   543 GMDYLASRRCIHRDLAARNVLVSD-DYVLKIADFGLARDI----QSTDYYRKNTNGRLPIKWMAP 602
            ||::|.|:..:|.|||.||:||.. .:..|:|:||||||:    ......:|....|:|::|..|
Zfish   225 GMEHLRSKMVVHCDLALRNILVGRFPWETKVAEFGLARDLTRMRSRRSSRKKQHKERVPLRWYPP 289

  Fly   603 ESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILM 667
            |..:..:|..|.|||:|||:|||:..:|..||..:.::||:...:.:|.:...|..|...:..::
Zfish   290 EYFRSNYYSFKGDVWAYGIVLWEMQMFGTLPYSNLSTSEEVVYNICAGLKNPIPRTCRPEMEQII 354

  Fly   668 RQCWHFNADDRPPFTEIVEYMDKLLQTKEDYLDVD 702
            |.||......||.||:||:.::.::::..||:.:|
Zfish   355 RDCWSDPYTSRPSFTDIVKILENIVESDGDYVHID 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
htl	NP_524394.2	Ig	112..191	CDD:299845
		IG_like	113..191	CDD:214653
		IG_like	205..289	CDD:214653
		PKc_like	404..692	CDD:304357	86/301 (29%)
		STYKc	416..688	CDD:214568	83/280 (30%)
si:ch211-167j9.5	XP_693602.5	TyrKc	109..375	CDD:197581	83/282 (29%)
si:ch211-167j9.5	XP_693602.5	PKc_like	118..376	CDD:304357	82/274 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910