Protein Alignment htl and PDGFRL

DIOPT Version :10

• Sequence 1: NP_524394.2
• Gene: htl / 42160
• FlyBaseID: FBgn0010389
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_006198.1
• Gene: PDGFRL / 5157
• HGNCID: 8805
• Length: 375
• Species: Homo sapiens
• Alignment Length: 80
• Identity: 25/80 - (31%)
• Similarity: 32/80 - (40%)
• Gaps: 15/80 - (18%)

  Fly   117 SGSLLTLNCHALGNP--EPNITWYRNGTVD---------WT---RGYGSLKR-NRWTLTMEDLVP 166
            ||..:::.|..||.|  |...||...|..|         |.   ||.|...| ::..:|:||...
Human   285 SGDDISVLCTVLGEPDVEVEFTWIFPGQKDERPVTIQDTWRLIHRGLGHTTRISQSVITVEDFET 349

  Fly   167 GDCGNYTCKVCNSLG 181
            .|.|.|.|...|..|
Human   350 IDAGYYICTAQNLQG 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htl	NP_524394.2	Ig	101..191	CDD:472250	25/80 (31%)
		Ig strand B	121..125	CDD:409353	0/3 (0%)
		Ig strand C	134..138	CDD:409353	1/3 (33%)
		Ig strand E	157..161	CDD:409353	0/3 (0%)
		Ig strand F	171..176	CDD:409353	2/4 (50%)
		Ig strand G	184..187	CDD:409353
		Ig	200..289	CDD:472250
		Ig strand B	216..220	CDD:409353
		Ig strand C	229..233	CDD:409353
		Ig strand E	255..259	CDD:409353
		Ig strand F	269..274	CDD:409353
		Ig strand G	282..285	CDD:409353
		Protein Kinases, catalytic domain	404..692	CDD:473864
PDGFRL	NP_006198.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..64
		IG_like	83..145	CDD:214653
		Ig	278..372	CDD:472250	25/80 (31%)
		Ig strand B	289..293	CDD:409404	0/3 (0%)
		Ig strand C	304..308	CDD:409404	1/3 (33%)
		Ig strand E	340..344	CDD:409404	0/3 (0%)
		Ig strand F	354..359	CDD:409404	2/4 (50%)
		Ig strand G	367..370	CDD:409404