Protein Alignment htl and Lmtk3

DIOPT Version :10

• Sequence 1: NP_524394.2
• Gene: htl / 42160
• FlyBaseID: FBgn0010389
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: XP_030098591.1
• Gene: Lmtk3 / 381983
• MGIID: 3039582
• Length: 1451
• Species: Mus musculus
• Alignment Length: 439
• Identity: 120/439 - (27%)
• Similarity: 186/439 - (42%)
• Gaps: 99/439 - (22%)

  Fly   292 SLHVLEAGVASGSL----HSTSF------------VYIFVFGGL---IFIFMTTLFVFYAIRKMK 337
            :|.:|.|..|||.|    |...|            |.:....||   ||:.:|.|.       .|
Mouse    33 ALILLAAVSASGCLASPAHPDGFALSRAPLAPPYAVVLISCSGLLAFIFLLLTCLC-------CK 90

  Fly   338 HEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGSM--------------DTMIMPVVRIQKQRTTV 388
            ...|..:..|            .|| |.|.||..              |..|:|:..:     ::
Mouse    91 RGDVRFKEFE------------NPE-GEDCSGEYTPPAEETSSSQSLPDVYILPLAEV-----SL 137

  Fly   389 LQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAEV----NNAIVAVKMVKEGH 449
            .....:| |.::...||.    |.|.||.....:|.|.||:|::.||    :.|.|.||.::...
Mouse   138 PMPAPQP-PHSDISTPLG----LSRQHLSYLQEIGSGWFGKVILGEVFSDYSPAQVVVKELRASA 197

  Fly   450 TDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDR 514
            ...:....:.|.:..:.: :|.|::..||.|.:..|..:|:|:...|:||.:|...||
Mouse   198 GPLEQRKFISEAQPYRSL-QHPNVLQCLGVCVETLPFLLIMEFCQLGDLKRYLRAQRP------- 254

  Fly   515 DSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLAR 579
            .....|..||..:.|   |.:...:||||:.:|.|...:|.|||.||.|::.|..::|.|:|||.
Mouse   255 PEGMSPELPPRDLRT---LQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAH 316

  Fly   580 DIQSTDYYRKNTNGRLPIKWMAPESLQEKF-------YDSKSDVWSYGILLWEIMTYGQQPYPTI 637
            .....|||.......:|::|.|||.|.|..       ...:|:|||.|:.|||:..:|.||| ..
Mouse   317 SNYKEDYYLTPERLWVPLRWAAPELLGELHGSFVLVDQSRESNVWSLGVTLWELFEFGAQPY-RH 380

  Fly   638 MSAEELYTYLMSGQRMEKPAKCSMNI------YILMRQCWHFNADDRPP 680
            :|.||:..:::..|.: |.|:..:.:      |.:::.||      |||
Mouse   381 LSDEEVLAFVVRQQHV-KLARPRLKLPYADYWYDILQSCW------RPP 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htl	NP_524394.2	Ig	101..191	CDD:472250
		Ig strand B	121..125	CDD:409353
		Ig strand C	134..138	CDD:409353
		Ig strand E	157..161	CDD:409353
		Ig strand F	171..176	CDD:409353
		Ig strand G	184..187	CDD:409353
		Ig	200..289	CDD:472250
		Ig strand B	216..220	CDD:409353
		Ig strand C	229..233	CDD:409353
		Ig strand E	255..259	CDD:409353
		Ig strand F	269..274	CDD:409353
		Ig strand G	282..285	CDD:409353
		Protein Kinases, catalytic domain	404..692	CDD:473864	90/294 (31%)
Lmtk3	XP_030098591.1	Protein Kinases, catalytic domain	162..437	CDD:473864	84/280 (30%)