Protein Alignment htl and Nrk

DIOPT Version :9

• Sequence 1: NP_524394.2
• Gene: htl / 42160
• FlyBaseID: FBgn0010389
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_477255.1
• Gene: Nrk / 36445
• FlyBaseID: FBgn0020391
• Length: 724
• Species: Drosophila melanogaster
• Alignment Length: 615
• Identity: 157/615 - (25%)
• Similarity: 245/615 - (39%)
• Gaps: 153/615 - (24%)

  Fly   155 NRWTLTME----DLVPGDCGNYTCKVCNSLGCIRHDTQVIVSDRVNHKPILMTGP----LNLTLV 211
            |.|.|..|    ::.....|::....|:||               .|....|..|    :.||.:
  Fly   161 NDWVLIEEKKERNMFIKSRGHFRLPNCSSL---------------PHYNASMRRPNCSYIGLTEL 210

  Fly   212 VNSTGSMHCK------YLSDLTSKKAWIFVPC----------------------HGMTNCSNNRS 248
            ..|..|..|:      |:..:...|:.|  ||                      .|...|.|
  Fly   211 KESEVSYDCRNGNGRFYMGTMNVSKSGI--PCQRWDTQYPHKHFQPPLVFHQLLEGENYCRN--- 270

  Fly   249 IIAEDKDQLDFVNVRMEQEGWYTC--------VESNSLGQSNSTAYLRVVRSLHVLEAGVASGSL 305
              |..::...:.....|...|..|        |:.|::.                |...:.....
  Fly   271 --AGGEEPHPWCYTVDESVRWQHCDIPMCPDYVDPNAVD----------------LNTPIKMEKF 317

  Fly   306 HSTSFVYIFVFGGLIFIFMTTLFVFYAIRKMKHEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGS 370
            .:.|.:::....|.:.|....|.:....:..||    |...:.....|.:..: ...||||..|:
  Fly   318 FTPSMIFLLAGIGFVAIVTLHLMILLVYKLSKH----KDYSQPAGAATAECSV-SMRGGGDCGGN 377

  Fly   371 MDTMIMPVVRIQKQRTTVLQNGN-----------EPAPFNEYEFPLDS----------------- 407
            ::|          .|.|:..|||           ..|..:.....|.:
  Fly   378 LNT----------SRETLGGNGNTNTLAKWGTIRSTATIHSNCVALTTVTNVSDAKGTKPNARLE 432

  Fly   408 NWELPRSHLVLGATLGEGAFGRVVMA-------EVNNAIVAVKMVKEGHTD------DDIASLVR 459
            ..|.||..:|...:||:||||||..|       :..:.:|||||:|:..:|      :..|.|:.
  Fly   433 KLEYPRGDIVYVRSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLA 497

  Fly   460 EMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPP 524
            |.:       |.||:.|||.|:...|:.::.||...|:|.:||....|:...|       .|:..
  Fly   498 EFD-------HPNIVRLLGVCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQ-------APTQD 548

  Fly   525 AHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRK 589
            ...:.|..|::.|..||.||.||:.|:.:|||||.||.|:::...:|||||||:..|...|||:.
  Fly   549 RLQLNELHLLQMAANIAAGMLYLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYYKG 613

  Fly   590 NTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRME 654
            :.|..:||:||..||:....:..:||||:|||.|||:.::..||| ..::.||:..|:..|..:.
  Fly   614 DENDFIPIRWMPLESILYNKFSLESDVWAYGICLWEVFSFALQPY-FGLTHEEVIKYIKEGNVLG 677

  Fly   655 KPAKCSMNIYILMRQCWHFNADDRPPFTEI 684
            .|....:::|.|||:||:....:||.|.||
  Fly   678 CPDNTPLSVYALMRRCWNRKPSERPGFAEI 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htl	NP_524394.2	Ig	112..191	CDD:299845	8/39 (21%)
		IG_like	113..191	CDD:214653	8/39 (21%)
		IG_like	205..289	CDD:214653	20/123 (16%)
		PKc_like	404..692	CDD:304357	106/311 (34%)
		STYKc	416..688	CDD:214568	102/282 (36%)
Nrk	NP_477255.1	CRD_FZ	67..212	CDD:295308	13/65 (20%)
		KR	217..299	CDD:214527	13/88 (15%)
		PTKc_Musk	435..713	CDD:133181	105/288 (36%)
		Pkinase_Tyr	441..707	CDD:285015	100/280 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455243
Domainoid	1	1.000	165	1.000	Domainoid score	I1208
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940