DRSC/TRiP Functional Genomics Resources

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Protein Alignment htl and Fgfrl1

DIOPT Version :9

Sequence 1:NP_524394.2 Gene:htl / 42160 FlyBaseID:FBgn0010389 Length:729 Species:Drosophila melanogaster
Sequence 2:NP_954545.1 Gene:Fgfrl1 / 360903 RGDID:735156 Length:529 Species:Rattus norvegicus


Alignment Length:297 Identity:81/297 - (27%)
Similarity:127/297 - (42%) Gaps:31/297 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 GARSQNKTPAITNNANQSSTSSADLDDGAADDDDNKADLPVNVS-SKPYWRNPKKM-SFLQTRPS 117
            |:.|.|.|..|.::.:....:..........:|      ||:.. ::|.:..|.|| ..:..||.
  Rat   102 GSLSVNYTLIIMDDISPGKENPGPGGSSGGQED------PVSQQWARPRFTQPSKMRRRVIARPV 160

  Fly   118 GSLLTLNCHALGNPEPNITWYRNGTVDWTRGYGSLKRNRWTLTMEDLVPGDCGNYTCKVCNSLGC 182
            ||.:.|.|.|.|:|.|:|.|.::............::.:|||::::|.|.|.|.|||:|.|..|.
  Rat   161 GSSVRLKCVASGHPRPDIMWMKDDQTLTRLEASEHRKKKWTLSLKNLKPEDSGKYTCRVSNRAGA 225

  Fly   183 IRHDTQVIVSDRVNHKPILM-TGPLNLTLVVNSTGSMHCKYLSDLTSKKAWIFVPCHGMTNCSNN 246
            |....:|.|..|...||:|. |.|:|.|:....|.|..||..||:.....|:....:|.....|:
  Rat   226 INATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGSEGRHNS 290

  Fly   247 RSIIAEDK------------------DQLDFVNVRMEQEGWYTCVESNSLGQSNSTAYLRVVRSL 293
            ...:...|                  ::|.....|.:..|.|.|:.:|::|.|..:|:|.|:...
  Rat   291 TIDVGGQKFVVLPTGDVWSRPDGSYLNKLLISRARQDDAGMYICLGANTMGYSFRSAFLTVLPDP 355

  Fly   294 HVLEAGVASGSLHSTSFVYIFVFG---GLIFIFMTTL 327
            ......||..| .:||..:..|.|   |.:||..|.|
  Rat   356 KPPGPPVAHSS-STTSLPWPVVIGIPAGAVFILGTVL 391

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
htlNP_524394.2 Ig 112..191 CDD:299845 27/78 (35%)
IG_like 113..191 CDD:214653 27/77 (35%)
IG_like 205..289 CDD:214653 23/101 (23%)
PKc_like 404..692 CDD:304357
STYKc 416..688 CDD:214568
Fgfrl1NP_954545.1 I-set 29..112 CDD:400151 4/9 (44%)
Ig strand A' 35..38 CDD:409353
Ig strand B 41..50 CDD:409353
Ig strand C 56..61 CDD:409353
Ig strand C' 64..67 CDD:409353
Ig strand D 72..77 CDD:409353
Ig strand E 78..84 CDD:409353
Ig strand F 91..99 CDD:409353
Ig strand G 102..112 CDD:409353 4/9 (44%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 117..152 6/40 (15%)
IgI_2_FGFRL1-like 143..234 CDD:409442 31/90 (34%)
Ig strand B 164..168 CDD:409442 1/3 (33%)
Ig strand C 177..181 CDD:409442 1/3 (33%)
Ig strand E 200..204 CDD:409442 3/3 (100%)
Ig strand F 214..219 CDD:409442 3/4 (75%)
Ig strand G 227..230 CDD:409442 0/2 (0%)
Ig 242..350 CDD:416386 25/107 (23%)
Ig strand A 242..245 CDD:409353 1/2 (50%)
Ig strand A' 249..253 CDD:409353 2/3 (67%)
Ig strand B 261..268 CDD:409353 3/6 (50%)
Ig strand C 272..279 CDD:409353 1/6 (17%)
Ig strand D 304..309 CDD:409353 0/4 (0%)
Ig strand E 317..322 CDD:409353 1/4 (25%)
Ig strand F 330..338 CDD:409353 3/7 (43%)
Ig strand G 341..349 CDD:409353 3/7 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 405..427
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0200
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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