DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment htl and tor

DIOPT Version :9

Sequence 1:NP_524394.2 Gene:htl / 42160 FlyBaseID:FBgn0010389 Length:729 Species:Drosophila melanogaster
Sequence 2:NP_476762.1 Gene:tor / 35717 FlyBaseID:FBgn0003733 Length:923 Species:Drosophila melanogaster


Alignment Length:523 Identity:134/523 - (25%)
Similarity:213/523 - (40%) Gaps:174/523 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   367 SSGSMDTMIMPVV---------------RIQKQRTTVLQNGNEPAPFNEYEFPL-DSNWEL---- 411
            |.|:|..:::.::               |..:.....||...:.|..:|:...| ||:..|    
  Fly   393 SEGNMVKLVLFIIVPICCILMLCSLTFCRRNRSEVQALQMDAKDAKASEFHLSLMDSSGLLVTLS 457

  Fly   412 --------------PRSHLVLGATLGEGAFGRVVMAEVNNAIVAVKMVKEGHTDDDIASLVREME 462
                          |.| ::|...|||||||.|.........||||::|:...|:|:.:...|::
  Fly   458 ANESLEVMDELEVEPHS-VLLQDVLGEGAFGLVRRGVYKKRQVAVKLLKDEPNDEDVYAFKCEIQ 521

  Fly   463 VMKIIGRHINIINLLGCCSQ-NGPLYVIVEYAPHGNLKDFLYK---------------------- 504
            ::|.:|:|.||:.::|..:: :..:.:::||...|:|::||.:                      
  Fly   522 MLKAVGKHPNIVGIVGYSTRFSNQMMLLIEYCSLGSLQNFLREEWKFRQEQNAIGLKKNLEQNVD 586

  Fly   505 NRPFGR---------------------------DQ------------------------------ 512
            ||.|.|                           ||                              
  Fly   587 NRRFNRLPRNSIHDRIEDINNSMLSTVEEESESDQTHSSRCETYTLTRITNAADNKGYGLEDIEN 651

  Fly   513 --------------DRDSSQPPPSP--------------------------------PAHVITEK 531
                          ||...:..|.|                                |...:...
  Fly   652 IGGSYIPKTAEAPKDRPKRKLKPQPKKDSKQDFKSDNKKRIFENKEYFDCLDSSDTKPRIPLKYA 716

  Fly   532 DLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKN-TNGRL 595
            ||:..|.|:|.||::||..:.:||||||||||:|.|..:|||||||:||:...:.|||: .:|:|
  Fly   717 DLLDIAQQVAVGMEFLAQNKVVHRDLAARNVLISVDRSIKIADFGLSRDVYHENVYRKSGGSGKL 781

  Fly   596 PIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCS 660
            ||||:|.|||..:.|.|:|||||:|:||:||.|.|..|||:: |..:|...|..|.||::|..|:
  Fly   782 PIKWLALESLTHQVYTSQSDVWSFGVLLYEITTLGGMPYPSV-SPSDLLQLLRQGHRMKRPEGCT 845

  Fly   661 MNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKEDYLDVDIANLDTPPSTSDEEEDETDNLQK 725
            ..::.||..||......||.|:.:...:..::....|.           |....:.:..|::..|
  Fly   846 QEMFSLMESCWSSVPSHRPTFSALKHRLGGMILATNDV-----------PERLKQLQAATESKLK 899

  Fly   726 WCN 728
            .|:
  Fly   900 SCD 902

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
htlNP_524394.2 Ig 112..191 CDD:299845
IG_like 113..191 CDD:214653
IG_like 205..289 CDD:214653
PKc_like 404..692 CDD:304357 121/433 (28%)
STYKc 416..688 CDD:214568 115/398 (29%)
torNP_476762.1 FN3 199..261 CDD:214495
STYKc 475..873 CDD:214568 115/398 (29%)
PTKc 479..873 CDD:270623 114/394 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24416
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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