Protein Alignment htl and Ddr

DIOPT Version :10

• Sequence 1: NP_524394.2
• Gene: htl / 42160
• FlyBaseID: FBgn0010389
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_001014474.3
• Gene: Ddr / 3346209
• FlyBaseID: FBgn0053531
• Length: 1054
• Species: Drosophila melanogaster
• Alignment Length: 396
• Identity: 109/396 - (27%)
• Similarity: 171/396 - (43%)
• Gaps: 94/396 - (23%)

  Fly   364 GGDSSGSMD-------TMIMPVVRIQKQRTTVLQNGNEPAPFNEYEFPLDSNW------------ 409
            |..||||:.       |....||.:.|.              :.|...:.:|:
  Fly   701 GSQSSGSLSSSTTAATTPTSGVVGVGKP--------------HHYNLDMSANFADINEERANCQV 751

  Fly   410 -ELPRSHLVLGATLGEGAFGRVVMAEVN--NA-IVAVKMVKEG---HTDDDIASLVREMEVMKII 467
             |.||..||:...||.|.||.:.:.|.|  || :|||..::.|   |...:..|..:::..:.
  Fly   752 QEFPRQSLVIVEKLGSGVFGELHLCETNVLNATLVAVATLRPGANDHLRKEFRSKAKQLAQLS-- 814

  Fly   468 GRHINIINLLGCCSQNGPLYVIVEYAPH--GNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITE 530
              ..|:..|:|.|.::.|:.::.:|: |  |:|..||               |...:..:.::.:
  Fly   815 --DPNVARLVGACLRDEPICIVQDYS-HCLGDLNQFL---------------QEHVAETSGLMAK 861

  Fly   531 KD-----LIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFG--LARDIQSTDYYR 588
            |.     |:..|.|||.||.:|.....:|||||.|:.::..:..:|:...|  :.|...::||.:
  Fly   862 KSLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQ 926

  Fly   589 -KNTNGR----LPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYG-QQPY------PTIMSAE 641
             :...||    :||:|||.||:....:.:||||||:.:.||||:|:. :|||      ..|.:..
  Fly   927 LEGFTGRQSQPMPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIG 991

  Fly   642 ELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKEDYLDVDIANL 706
            .:|......:.:..|..|...||.||.:||..:...||.|.||..|    ||.|         ||
  Fly   992 LIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESSRPSFREIHLY----LQRK---------NL 1043

  Fly   707 DTPPST 712
            ...|.|
  Fly  1044 GFKPQT 1049

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htl	NP_524394.2	Ig	101..191	CDD:472250
		Ig strand B	121..125	CDD:409353
		Ig strand C	134..138	CDD:409353
		Ig strand E	157..161	CDD:409353
		Ig strand F	171..176	CDD:409353
		Ig strand G	184..187	CDD:409353
		Ig	200..289	CDD:472250
		Ig strand B	216..220	CDD:409353
		Ig strand C	229..233	CDD:409353
		Ig strand E	255..259	CDD:409353
		Ig strand F	269..274	CDD:409353
		Ig strand G	282..285	CDD:409353
		Protein Kinases, catalytic domain	404..692	CDD:473864	92/327 (28%)
Ddr	NP_001014474.3	FA58C	109..261	CDD:238014
		PTKc_DDR	753..1040	CDD:270644	92/310 (30%)