Protein Alignment htl and Wsck

DIOPT Version :9

• Sequence 1: NP_524394.2
• Gene: htl / 42160
• FlyBaseID: FBgn0010389
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_733018.1
• Gene: Wsck / 318600
• FlyBaseID: FBgn0046685
• Length: 791
• Species: Drosophila melanogaster
• Alignment Length: 618
• Identity: 136/618 - (22%)
• Similarity: 244/618 - (39%)
• Gaps: 156/618 - (25%)

  Fly   152 LKRNRWTLTMEDLVPGDCGNYTCKVCNSLGCIRHDTQVIVSDRVNHKPILMTGPLNLTLVVNSTG 216
            |.|...|:|:|                 |..||:|                .|||:..||:
  Fly   258 LSRTDRTVTIE-----------------LSPIRND----------------NGPLSKLLVI---- 285

  Fly   217 SMHCKYLSDLTSKK-------AWIFVPCHGM----------TNCSNNRS---IIAEDKDQLDFVN 261
               .:|:.:..|:.       :|......|:          ....:||:   ::.:.|....|.|
  Fly   286 ---VEYVDNALSQPFDAQLLGSWQQAQQDGVPYYIAAELDYDRPEDNRTRRFVVGDGKRYGRFTN 347

  Fly   262 VRMEQEGWYTCVESNSLGQSNS------TAYLRVVRSLHV----------LEAGVASGSLHSTSF 310
            ..::|...:..:   |||..::      |.|.|.....||          .|.|.:|....:.:.
  Fly   348 KPLDQPDAHVHI---SLGLVSTLEGVTKTMYSRGTHDQHVTSLDDFSYATFEKGQSSVVALAVTC 409

  Fly   311 VYIFVFGGLIFIFMTTLFVFYAIRKMKHEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGSMDTMI 375
            |   :||..:.:   :|..::.:|    .|..:.|..|              ||.....::.|.|
  Fly   410 V---IFGSCLLL---SLIAYFYLR----YKTCRGRRLT--------------GGNTHEMTLQTPI 450

  Fly   376 MPVVRIQKQRTTVLQNGNEPAPFNEYEF-----PLDSNWE-LPRSHLVLGA--TLGEGAFGRVVM 432
                 |:::....|.. ::|.|.:...|     .|...:| :||:.|.|..  .:|:|.||.::.
  Fly   451 -----IERENNGYLVE-DDPLPHSPENFKQQLQQLVEGYERIPRNALRLNVNDVIGDGRFGEIIT 509

  Fly   433 AEVNNAIVAVKMVKEGHTDDDI-----ASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEY 492
            .:|:....|..........||:     |.|:||:..:..:.|..::::..|..:.....|:|.|
  Fly   510 GKVSTNDFARDCTLHVLCLDDLNGTTQAQLLRELRQLSQLKRQEHLLDFYGVSASPDWFYLIFE- 573

  Fly   493 APHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDL 557
            ....:||..|.::|...           |||....::|:.::::.:::|..|:||:|.:.:||.|
  Fly   574 QQRMSLKRKLVESRLMA-----------PSPRLTSLSEQLVLQWIYELASAMNYLSSCQVVHRQL 627

  Fly   558 AARNVLVSDDYVLKIADFG------LARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDS-KSD 615
            .:.:|.|:.|:.||::.||      :||  |..|:.|          |:|||.|:.:.:.| :||
  Fly   628 CSHSVFVTSDFKLKLSVFGPLPYMNIAR--QQPDHNR----------WLAPEVLRHQHHHSTRSD 680

  Fly   616 VWSYGILLWEIMTYGQQPYP-TIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRP 679
            |||...:.||....|..||. .:.|.::|...:.:..|..:||....::|.|:..||.....:|.
  Fly   681 VWSLACVAWECCALGGTPYANAVASNQQLLEAIRAAVRPAQPAYVYGDLYQLLLNCWQLEPSERS 745

  Fly   680 PFTEIVEYMDKLLQTKEDYLDVD--IANLDTPP 710
            ...::...:.:|:.:....|..|  ...|||.|
  Fly   746 SCEDVAFGVRQLMTSPRHALSFDRVAGGLDTLP 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htl	NP_524394.2	Ig	112..191	CDD:299845	9/38 (24%)
		IG_like	113..191	CDD:214653	9/38 (24%)
		IG_like	205..289	CDD:214653	19/109 (17%)
		PKc_like	404..692	CDD:304357	77/303 (25%)
		STYKc	416..688	CDD:214568	73/286 (26%)
Wsck	NP_733018.1	WSC	42..115	CDD:280068
		fn3	130..222	CDD:278470
		TyrKc	493..746	CDD:197581	72/276 (26%)
		PTKc	497..750	CDD:270623	71/276 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810