Protein Alignment htl and Mst1r

DIOPT Version :10

• Sequence 1: NP_524394.2
• Gene: htl / 42160
• FlyBaseID: FBgn0010389
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: XP_006511717.1
• Gene: Mst1r / 19882
• MGIID: 99614
• Length: 1406
• Species: Mus musculus
• Alignment Length: 397
• Identity: 121/397 - (30%)
• Similarity: 196/397 - (49%)
• Gaps: 67/397 - (16%)

  Fly   366 DSSGSMDTMIMPVVRIQKQRTTVLQNGNEPAPFNEYEFPLD-------SNWELPRSHLVL--GAT 421
            :||.|.|...:|::|.:..|   ||:             ||       .:..:|...:|:  ...
Mouse  1017 ESSESRDGTSVPLLRTESIR---LQD-------------LDRMLLAEVKDVLIPHEQVVIHTDQV 1065

  Fly   422 LGEGAFGRVVMAEV-----NNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLG-CC 480
            :|:|.||.|...|.     |....|:|.:.......::.:.:||..:|:.: .|.||:.|:| ..
Mouse  1066 IGKGHFGVVYHGEYTDGAQNQTHCAIKSLSRITEVQEVEAFLREGLLMRGL-HHPNILALIGIML 1129

  Fly   481 SQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPP-------------------PSPPAH 526
            ...|...|::.|..||:|..|:       |...|.|...|                   |..|
Mouse  1130 PPEGLPRVLLPYMRHGDLLHFI-------RSPQRVSDHCPGWEVSASTHPCLRSPVTLCPQNP-- 1185

  Fly   527 VITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYY--RK 589
              |.|||:.|..|:|.||:|||.::.:||||||||.::.:.:.:|:|||||||.:...:||  |:
Mouse  1186 --TVKDLVSFGLQVACGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARGVLDKEYYSVRQ 1248

  Fly   590 NTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRME 654
            :.:.|||:||||.||||...:.:||||||:|:||||::|.|..|||.| ...:|..:|..|:|:.
Mouse  1249 HRHARLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYPHI-DPFDLSHFLAQGRRLP 1312

  Fly   655 KPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQT--KEDYLDVDIANLDTPPSTSDEEE 717
            :|..|..::|.:|.:||..:...||.|..:|..:.:::.:  .:.|:.:..|.::..|...|:..
Mouse  1313 QPEYCPDSLYHVMLRCWEADPAARPTFRALVLEVKQVVASLLGDHYVQLTAAYVNVGPRAVDDGS 1377

  Fly   718 DETDNLQ 724
            ...:.:|
Mouse  1378 VPPEQVQ 1384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htl	NP_524394.2	Ig	101..191	CDD:472250
		Ig strand B	121..125	CDD:409353
		Ig strand C	134..138	CDD:409353
		Ig strand E	157..161	CDD:409353
		Ig strand F	171..176	CDD:409353
		Ig strand G	184..187	CDD:409353
		Ig	200..289	CDD:472250
		Ig strand B	216..220	CDD:409353
		Ig strand C	229..233	CDD:409353
		Ig strand E	255..259	CDD:409353
		Ig strand F	269..274	CDD:409353
		Ig strand G	282..285	CDD:409353
		Protein Kinases, catalytic domain	404..692	CDD:473864	107/323 (33%)
Mst1r	XP_006511717.1	Sema_RON	29..525	CDD:200540
		PSI	528..570	CDD:396154
		IPT	571..685	CDD:472823
		IPT_plexin_repeat2	686..770	CDD:238584
		IPT	771..864	CDD:214657
		Protein Kinases, catalytic domain	1064..1352	CDD:473864	103/300 (34%)