Protein Alignment htl and old-2

DIOPT Version :9

• Sequence 1: NP_524394.2
• Gene: htl / 42160
• FlyBaseID: FBgn0010389
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_496123.1
• Gene: old-2 / 191738
• WormBaseID: WBGene00003863
• Length: 498
• Species: Caenorhabditis elegans
• Alignment Length: 518
• Identity: 149/518 - (28%)
• Similarity: 237/518 - (45%)
• Gaps: 108/518 - (20%)

  Fly   271 TCVESN-SLGQSNSTAYLRVVRSLHVLEAGVASGSLHSTSFVYIFVFGGLIFIFMTTLFVFYAIR 334
            :|...| :||::...::.||.|:....|.|.::             ...:|||.:.::||..||.
 Worm    18 SCYARNLTLGRNFEDSFKRVPRASEKNELGDSN-------------VQQIIFISLYSVFVALAIG 69

  Fly   335 KMKHEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGSMDTMIMPVVRIQKQRTTVLQNGNEPAPF- 398
            .....|..|.:              |.:...:.|...:.::.|....||:|.:......||.|:
 Worm    70 ICCLIKAYKSK--------------KRQLPANRSKGNEYLLEPTTADQKKRYSNNIVPPEPTPYP 120

  Fly   399 ---NEYEFPLD----SNWELPRS--------------------------HLVLGATLGEGAFGRV 430
               .|.:|...    ||.|.|..                          .:..|..||.|.||.:
 Worm   121 ITSGEDDFGKTPSRLSNEECPPELKLAPINDRIKYLHYYAEVEINEEDLDISKGRPLGSGEFGII 185

  Fly   431 VMA----------EVNNAI-VAVK--MVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQ 482
            ...          |..:.: ||||  :.:..|...::  :..|::||..:|:|.||:.|:|..:.
 Worm   186 RKGFLRSKNSKNKETESRLEVAVKSPLNEYNHIQQEL--IYDELKVMCAVGKHPNILALVGGITI 248

  Fly   483 NGPLYVIVEYAPHGNLKDFLYKN-RPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDY 546
            .....:|.|...:|:|..||.|| |.|..||   .:..|..|...::   ||:.||.|||:||:|
 Worm   249 GEKRMIISELVENGDLLSFLRKNRRNFTIDQ---LAFEPEKPSLGLV---DLVSFAFQIAKGMEY 307

  Fly   547 LASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYR-KNTNGRLPIKWMAPESLQEKFY 610
            |....|:|||||.||||:..:.|::||||||||..::.|||: ::.:..|||.||||||:.:..:
 Worm   308 LIHVPCVHRDLALRNVLIKGNMVIRIADFGLARRHKNKDYYKTQSVDTPLPIHWMAPESIDKLLF 372

  Fly   611 DSKSDVWSYGILLWEIMTYGQQPYPTIMSAEE-------LYTYLMSGQRMEKPAKCSMNIYILMR 668
            ..||||||||:.|:|:.:.|:.||..::..:|       :..||..|:|:.:||.....||.:|:
 Worm   373 TQKSDVWSYGVCLYELFSLGKSPYKNVIKYDERDSYCKYVLAYLNEGKRLAQPAHADAEIYNVMK 437

  Fly   669 QCWHFNADDRPPFTEIVEYMDKLLQT--KEDYLDVDIANLDTPPSTSDEEEDETDN---LQKW 726
            .||..:.:.|..|.:.:|:.:|.|:|  .|.:||:           :.:...||:|   |..|
 Worm   438 LCWDLDMNSRTTFLDCIEFFEKELKTTSNEYFLDL-----------TRKLRSETNNQLRLSNW 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htl	NP_524394.2	Ig	112..191	CDD:299845
		IG_like	113..191	CDD:214653
		IG_like	205..289	CDD:214653	4/18 (22%)
		PKc_like	404..692	CDD:304357	110/339 (32%)
		STYKc	416..688	CDD:214568	105/293 (36%)
old-2	NP_496123.1	PTKc	175..458	CDD:270623	104/290 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810