DRSC/TRiP Functional Genomics Resources

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Protein Alignment htl and zig-13

DIOPT Version :10

Sequence 1:NP_524394.2 Gene:htl / 42160 FlyBaseID:FBgn0010389 Length:729 Species:Drosophila melanogaster
Sequence 2:NP_497161.1 Gene:zig-13 / 188571 WormBaseID:WBGene00020546 Length:352 Species:Caenorhabditis elegans


Alignment Length:188 Identity:38/188 - (20%)
Similarity:60/188 - (31%) Gaps:73/188 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   106 PKKMSFLQ--TRPSGSLLTLNC-HALGNPEPNITWYRNGTVD-----------------WTRGYG 150
            |.:.:||:  |:.:||.:.:|. .|:.:         :||.|                 ||||.|
 Worm    58 PPETAFLEYRTKKTGSFVRINYQRAISD---------DGTFDSGVFYNVSLTEDIEFLCWTRGQG 113

  Fly   151 --SLKRNRWTLTMEDLVPGDCGNYTCKVCNSLGCIRHDTQVIVSDRVN------HKPI------- 200
              |.|...       :..|....:    .|..|..|....|...|.||      |..|       
 Worm   114 HPSFKHIH-------VADGPSKAF----YNVGGAPRFQKSVYEQDTVNLFCAIPHSAINWKVSWR 167

  Fly   201 ----LMTGPLNLTLVVNSTGSMHCKYLSDLTSKKAWIFVPCHGMTNCSNNRSIIAEDK 254
                ..|..|::|.:::.....|...:.::|..         |:..|     :|..||
 Worm   168 LENSNSTSDLSVTTLIDGNSKYHVTTVKNITKS---------GVYTC-----VIEADK 211

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
htlNP_524394.2 Ig 101..191 CDD:472250 23/106 (22%)
Ig strand B 121..125 CDD:409353 0/3 (0%)
Ig strand C 134..138 CDD:409353 0/3 (0%)
Ig strand E 157..161 CDD:409353 0/3 (0%)
Ig strand F 171..176 CDD:409353 0/4 (0%)
Ig strand G 184..187 CDD:409353 1/2 (50%)
Ig 200..289 CDD:472250 11/66 (17%)
Ig strand B 216..220 CDD:409353 0/3 (0%)
Ig strand C 229..233 CDD:409353 0/3 (0%)
Ig strand E 255..259 CDD:409353 38/188 (20%)
Ig strand F 269..274 CDD:409353
Ig strand G 282..285 CDD:409353
Protein Kinases, catalytic domain 404..692 CDD:473864
zig-13NP_497161.1 Ig 227..301 CDD:472250
Ig strand B 251..255 CDD:409442
Ig strand C 264..268 CDD:409442
Ig strand E 276..279 CDD:409442
Ig strand F 285..290 CDD:409442
Blue background indicates that the domain is not in the aligned region.

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