Protein Alignment htl and kin-30

DIOPT Version :10

• Sequence 1: NP_524394.2
• Gene: htl / 42160
• FlyBaseID: FBgn0010389
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_506771.3
• Gene: kin-30 / 180032
• WormBaseID: WBGene00002211
• Length: 458
• Species: Caenorhabditis elegans
• Alignment Length: 415
• Identity: 130/415 - (31%)
• Similarity: 205/415 - (49%)
• Gaps: 44/415 - (10%)

  Fly   313 IFVFGGLIFIFMTTLFVFYAIRKMKHEKVLK---QRIETVHQWTKKVIIFKPEGGGDSSGSMDTM 374
            :|::|.|..||:|..|    :|::......|   :|....:.:.|..:    :....||..:|..
 Worm    36 LFIYGVLSIIFVTICF----LRRIYRSSATKNGNRRYLVQNTYVKAQL----DTNSSSSLPVDKE 92

  Fly   375 IMPVVRIQKQR--TTVLQNGNEPAPFNEYEFPLDSNWELPRSHL-VLGATLGEGAFGRVVMA--- 433
            |:..:.|.::.  .|..|..||.|   || .|.:..:|:...|| |.....|:|.||:|..|
 Worm    93 IIETISINEETPIITDYQPLNERA---EY-LPYNPAFEIHSEHLDVFEKQFGQGNFGKVNKALLK 153

  Fly   434 -------EVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPL----- 486
                   ||....||||...:.........::.|:::|..||:|.|::.::|..::...:
 Worm   154 LINQKTGEVVRMDVAVKKPADSTDKSQDKLILDEIKLMCAIGKHPNVLAIVGAITKQEKVIGREH 218

  Fly   487 -YVIVEYAPHGNLKDFLYKNRPFG-RDQ----DRDSSQPPPSPPAHVITEKDLIKFAHQIARGMD 545
             .|:.|:...|:|:..| |..|:. .|:    ||...|...|.....::..||..||:|||.||:
 Worm   219 NLVVTEFVEGGDLRSVL-KYTPYTFHDELTSTDRTGGQMVNSDIFDELSTSDLYSFAYQIANGME 282

  Fly   546 YLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRK--NTNGRLPIKWMAPESLQEK 608
            |||::.|:|||||.|||.|..:.:::|.||||||......|||.  |.:..|||.|:|||...|.
 Worm   283 YLAAKPCVHRDLALRNVFVKRNKMIRIGDFGLARHHSKKSYYRMQCNPDTPLPIFWLAPECFNES 347

  Fly   609 FYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAE--ELYTYLMSGQRMEKPAKCSMNIYILMRQCW 671
            .:...:||||||:.|:|:.:.|:.||..:.::.  ::..||..|.|:..|..|:..||..|..||
 Worm   348 KFTEMTDVWSYGVCLFELFSLGESPYKKLHNSPSYDVVHYLKKGYRLSAPRYCNAEIYEFMLYCW 412

  Fly   672 HFNADDRPPFTEIVEYMDKLLQTKE 696
            :.:|..||.|||..::...|:..|:
 Worm   413 NIDATLRPKFTECKDFCKSLITRKK 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htl	NP_524394.2	Ig	101..191	CDD:472250
		Ig strand B	121..125	CDD:409353
		Ig strand C	134..138	CDD:409353
		Ig strand E	157..161	CDD:409353
		Ig strand F	171..176	CDD:409353
		Ig strand G	184..187	CDD:409353
		Ig	200..289	CDD:472250
		Ig strand B	216..220	CDD:409353
		Ig strand C	229..233	CDD:409353
		Ig strand E	255..259	CDD:409353
		Ig strand F	269..274	CDD:409353
		Ig strand G	282..285	CDD:409353
		Protein Kinases, catalytic domain	404..692	CDD:473864	105/313 (34%)
kin-30	NP_506771.3	TyrKc	134..428	CDD:197581	101/294 (34%)