Protein Alignment htl and CSK

DIOPT Version :10

• Sequence 1: NP_524394.2
• Gene: htl / 42160
• FlyBaseID: FBgn0010389
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_004374.1
• Gene: CSK / 1445
• HGNCID: 2444
• Length: 450
• Species: Homo sapiens
• Alignment Length: 40
• Identity: 9/40 - (22%)
• Similarity: 18/40 - (45%)
• Gaps: 8/40 - (20%)

  Fly     3 EEESIRLDVSSVSSDKVATEQRDDKGPLKLTEPRKRMRED 42
            |:|    :..:.:..:||.:..||....|    :::..||
Human    79 EDE----EAEAPTGKRVAEDDEDDDVDTK----KQKTEED 110

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
htl	NP_524394.2	Ig	101..191	CDD:472250
		Ig strand B	121..125	CDD:409353
		Ig strand C	134..138	CDD:409353
		Ig strand E	157..161	CDD:409353
		Ig strand F	171..176	CDD:409353
		Ig strand G	184..187	CDD:409353
		Ig	200..289	CDD:472250
		Ig strand B	216..220	CDD:409353
		Ig strand C	229..233	CDD:409353
		Ig strand E	255..259	CDD:409353
		Ig strand F	269..274	CDD:409353
		Ig strand G	282..285	CDD:409353
		Protein Kinases, catalytic domain	404..692	CDD:473864
CSK	NP_004374.1	Interaction with PTPN22. /evidence=ECO:0000250|UniProtKB:P41241	9..70
		SH3_CSK	11..67	CDD:212703
		SH2_csk_like	78..175	CDD:198190	9/40 (23%)
		PTKc_Csk	188..443	CDD:133213