Protein Alignment CG7794 and TUBB1

DIOPT Version :9

• Sequence 1: NP_650674.1
• Gene: CG7794 / 42159
• FlyBaseID: FBgn0038565
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_110400.1
• Gene: TUBB1 / 81027
• HGNCID: 16257
• Length: 451
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 158/455 - (34%)
• Similarity: 253/455 - (55%)
• Gaps: 18/455 - (3%)

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGI-LANGRLTQSPMDDSFLTFFEFTSHQPCVQPRLVMID 69
            ||:.|.|||.|.||....||:...|||| ||......|.:....::.:...::.....||.|::|
Human     3 EIVHIQIGQCGNQIGAKFWEMIGEEHGIDLAGSDRGASALQLERISVYYNEAYGRKYVPRAVLVD 67

  Fly    70 TEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRCRNLRG 134
            .||..:|.||:.....||.||:.:.|...:|:|:|:|:....:||::..:..:|..::.|..|:|
Human    68 LEPGTMDSIRSSKLGALFQPDSFVHGNSGAGNNWAKGHYTEGAELIENVLEVVRHESESCDCLQG 132

  Fly   135 FLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHFSMDCA 199
            |.:..::|||:|||:||.:|.::.|::..:: :..|.|.|||.:|..:||||||:|:.|..::.|
Human   133 FQIVHSLGGGTGSGMGTLLMNKIREEYPDRI-MNSFSVMPSPKVSDTVVEPYNAVLSIHQLIENA 196

  Fly   200 DVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTNLVPYP 264
            |..|.:|||||||||..||.:..|||.:||.:::..:|..|.|.||.|......::|..|:||:|
Human   197 DACFCIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPFP 261

  Fly   265 RIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDIAPNEI 329
            |:|:.:..:|||......|:..:|.|:||.|.|...|.|..|:...|:|:....::||.::..|:
Human   262 RLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNTMAACDLRRGRYLTVACIFRGKMSTKEV 326

  Fly   330 NTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAWCRLVN 394
            :..|.:::...|..||:|.|...|:.|..:||   .|..:|.|     .|.|||.|:..:.|:..
Human   327 DQQLLSVQTRNSSCFVEWIPNNVKVAVCDIPP---RGLSMAAT-----FIGNNTAIQEIFNRVSE 383

  Fly   395 KFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEV-DASA-------PTSRRDSDPEE 451
            .|..:::|:|||:.|..||::...|.||..||..||.:|.:. ||.|       .|...:.:||:
Human   384 HFSAMFKRKAFVHWYTSEGMDINEFGEAENNIHDLVSEYQQFQDAKAVLEEDEEVTEEAEMEPED 448

  Fly   452  451
            Human   449  448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	152/430 (35%)
		PTZ00335	6..439	CDD:185562	153/434 (35%)
TUBB1	NP_110400.1	PTZ00010	1..428	CDD:240228	152/433 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	432..451		3/17 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810