DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7794 and tubb4b

DIOPT Version :9

Sequence 1:	NP_650674.1	Gene:	CG7794 / 42159	FlyBaseID:	FBgn0038565	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	XP_012825219.1	Gene:	tubb4b / 779904	XenbaseID:	XB-GENE-969447	Length:	474	Species:	Xenopus tropicalis

Alignment Length:	478	Identity:	151/478 - (31%)
Similarity:	256/478 - (53%)	Gaps:	40/478 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRL---TQSPMDDSFLTFFEFTSHQPC------- 60
            ||:.:..||.|.||....||:...||||...|..   :...::...:.:.|.|....|
Frog     3 EIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGEWECRFCSVGG 67

  Fly    61 --------------------VQPRLVMIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFAR 105
                                ..||.|::|.||..:|.:|:|.:..:|.||..:.|:..:|:|:|:
Frog    68 CWSSRIPGMPYILLPFAGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAK 132

  Fly   106 GYNLMASELLDRSMNAIRRVADRCRNLRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEF 170
            |:....:||:|..::.:|:.|:.|..|:||.:..::|||:|||:||.::.::.|::..:: :..|
Frog   133 GHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRI-MNTF 196

  Fly   171 LVYPSPSISPVIVEPYNALLAAHFSMDCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQV 235
            .|.|||.:|..:||||||.|:.|..::..|.::.:|||||||||..||.:..|||.:||.:::..
Frog   197 SVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSAT 261

  Fly   236 VSSFTASQRFGGGSTVSFQELQTNLVPYPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMS 300
            :|..|...||.|......::|..|:||:||:|:.:..:|||......|:..::..:||.|.|...
Frog   262 MSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAK 326

  Fly   301 NQMVRCNPSHGKYMASVLLYRGDIAPNEINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVP 365
            |.|..|:|.||:|:....::||.::..|::..:.|::...|..||:|.|...|..|..:||   .
Frog   327 NMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---R 388

  Fly   366 GGDLAPTNRACVAISNNTNIRIAWCRLVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLV 430
            |..::.|     .|.|:|.|:..:.|:..:|..:::|:||::.|.|||::|..|.||..|:..||
Frog   389 GLKMSAT-----FIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLV 448

  Fly   431 HDYLEV-DASAPTSRRDSDPEED 452
            .:|.:. ||:|.......:.||:
Frog   449 SEYQQYQDATAEEEGEFEEGEEE 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	146/459 (32%)
CG7794	NP_650674.1	PTZ00335	6..439	CDD:185562	147/463 (32%)
tubb4b	XP_012825219.1	PLN00220	1..459	CDD:215107	148/464 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910