Protein Alignment CG7794 and TUBB2A

DIOPT Version :9

• Sequence 1: NP_650674.1
• Gene: CG7794 / 42159
• FlyBaseID: FBgn0038565
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001060.1
• Gene: TUBB2A / 7280
• HGNCID: 12412
• Length: 445
• Species: Homo sapiens
• Alignment Length: 452
• Identity: 149/452 - (32%)
• Similarity: 254/452 - (56%)
• Gaps: 20/452 - (4%)

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRLTQSPMDDSFL------TFFEFTSHQPCVQPR 64
            ||:.|..||.|.||....||:...||||...|    |...||.|      .::...:....| ||
Human     3 EIVHIQAGQCGNQIGAKFWEVISDEHGIDPTG----SYHGDSDLQLERINVYYNEAAGNKYV-PR 62

  Fly    65 LVMIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRC 129
            .:::|.||..:|.:|:|.:..:|.||..:.|:..:|:|:|:|:....:||:|..::.:|:.::.|
Human    63 AILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESC 127

  Fly   130 RNLRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHF 194
            ..|:||.:..::|||:|||:||.::.::.|::..:: :..|.|.|||.:|..:||||||.|:.|.
Human   128 DCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRI-MNTFSVMPSPKVSDTVVEPYNATLSVHQ 191

  Fly   195 SMDCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTN 259
            .::..|.::.:|||||||||..||.:..|||.:||.:::..:|..|...||.|......::|..|
Human   192 LVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVN 256

  Fly   260 LVPYPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDI 324
            :||:||:|:.:..:|||......|:..::..:||.|.|...|.|..|:|.||:|:....::||.:
Human   257 MVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRM 321

  Fly   325 APNEINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAW 389
            :..|::..:.|::...|..||:|.|...|..|..:||   .|..::.|     .|.|:|.|:..:
Human   322 SMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMSAT-----FIGNSTAIQELF 378

  Fly   390 CRLVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEVDASAPTSRRDSDPEE 451
            .|:..:|..:::|:||::.|.|||::|..|.||..|:..||.:|.:...:....:.:.:.||
Human   379 KRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEE 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	147/435 (34%)
		PTZ00335	6..439	CDD:185562	147/438 (34%)
TUBB2A	NP_001060.1	PLN00220	1..430	CDD:215107	147/440 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..445		3/19 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810