Protein Alignment CG7794 and TUBA3C

DIOPT Version :9

• Sequence 1: NP_650674.1
• Gene: CG7794 / 42159
• FlyBaseID: FBgn0038565
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_005992.1
• Gene: TUBA3C / 7278
• HGNCID: 12408
• Length: 450
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 234/449 - (52%)
• Similarity: 315/449 - (70%)
• Gaps: 6/449 - (1%)

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRL----TQSPMDDSFLTFFEFTSHQPCVQPRLV 66
            |.|.||:|||||||.||||||:||||||..:|::    |....||||.|||..|.....| ||.|
Human     3 ECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHV-PRAV 66

  Fly    67 MIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRCRN 131
            .:|.||||:||:|||:||.||||:.|||||:|:.:|:|||:..:..|::|..::.||::||.|..
Human    67 FVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTG 131

  Fly   132 LRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHFSM 196
            |:|||:|.:.|||:|||..:.:||||..|:||| :.:||.:||:|.:|..:|||||::|..|.::
Human   132 LQGFLIFHSFGGGTGSGFASLLMERLSVDYGKK-SKLEFAIYPAPQVSTAVVEPYNSILTTHTTL 195

  Fly   197 DCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTNLV 261
            :.:|.:|:|||||:||||...|::..||||||||:|.|:|||.|||.||.|...|...|.|||||
Human   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260

  Fly   262 PYPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDIAP 326
            ||||||:||..|||::....:....:|.|::|..||:.:||||:|:|.||||||..:|||||:.|
Human   261 PYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVP 325

  Fly   327 NEINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAWCR 391
            .::|.|:..||..|:.:||||.|||||:|::..||..|||||||...||...:||.|.|..||.|
Human   326 KDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390

  Fly   392 LVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEVDASAPTSRRDSDPE 450
            |.:|||.:|.:||||:.|||||:|||.|:||.|::..|..||.||...:..:..:...|
Human   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEAEEGEE 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	231/433 (53%)
		PTZ00335	6..439	CDD:185562	233/436 (53%)
TUBA3C	NP_005992.1	PTZ00335	1..440	CDD:185562	233/438 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S25
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D514396at2759
OrthoFinder	1	1.000	-	-		FOG0000082
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.770