DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7794 and Tubd1

DIOPT Version :9

Sequence 1:	NP_650674.1	Gene:	CG7794 / 42159	FlyBaseID:	FBgn0038565	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001185974.1	Gene:	Tubd1 / 56427	MGIID:	1891826	Length:	486	Species:	Mus musculus

Alignment Length:	502	Identity:	115/502 - (22%)
Similarity:	216/502 - (43%)	Gaps:	98/502 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IIQIHIGQAGVQIANACWE-LFCLEH---GILA--NGRLTQSPMDDSFLTFFEFTSHQPCVQPRL 65
            |:.:.:||.|.||....:: ||...|   |:.:  :....|:...:.|  |.|..:..|..  |.
Mouse     3 IVTVQLGQCGNQIGFEVFDALFRDSHCSQGLCSKRDNEAYQASCRERF--FREEENGVPVA--RA 63

  Fly    66 VMIDTEPTVIDE-----IRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRV 125
            |::|.||.||::     .::|.:.  :...|....|..||:|:|.||::...:..:..||.|:..
Mouse    64 VLVDMEPKVINQTLSKAAQSGRWN--YGQHTSFCQKQGSGNNWAYGYSVHGPKHEESIMNLIQTE 126

  Fly   126 ADRCRNLRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALL 190
            .::|.:|.||.:..::.||:|||||..:.::|.:.:...:.:.: :::|. ....|||:.||::|
Mouse   127 VEKCDSLSGFFIIMSMAGGTGSGLGAFVTQKLQDQYSSSLKMNQ-IIWPY-GTGEVIVQNYNSIL 189

  Fly   191 AAHFSMDCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSS-----FTASQRFG---- 246
            ........:|...|.:|:|::.|||..:|:...::.:||:::|..:.|     ::....|.
Mouse   190 TLSHLYRSSDALLIHENDAVHKICAKRMNIKQISFRDLNQVLAHQLGSVFQPTYSEDSSFHYRRN 254

  Fly   247 ----------------------GGSTVSFQ----ELQTNLVPYPR----------------IHYP 269
                                  ..:.:||.    :|..:|||:|.                :.|.
Mouse   255 PLDSGTVGPQACLMPRIFVWSLSATNLSFYPQTGDLMEHLVPHPEFKMLGVRNIPQMSAASLAYS 319

  Fly   270 LINYAPLVPISHSQFVNMSTAQL-TGQCFQMSNQMVRCNPSHGKYMASVLLYRGDIAPNEINTAL 333
            ...:|.|  :.|.:.:.:|:|:: .|..:|:...:... |..||..|.        ..:..||:|
Mouse   320 AFTWAGL--LKHLRQMLISSAKMEEGINWQVRPPLTGL-PPIGKASAH--------KEHHFNTSL 373

  Fly   334 EN--IKRNRSFRFVDWSPTGFK---IGVSPMPPYYVPGGDLAPTNRA-------CVAISNNTNIR 386
            .|  :.|.|.....|  ..|||   :..|.:.|  |....:..|.||       ...:||:..:.
Mouse   374 ANLVVLRGREVHSAD--VEGFKDPALYTSWLEP--VDAFSVWKTQRAFDKYEKSAALVSNSQLLV 434

  Fly   387 IAWCRLVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDY 433
            .....:|.|...::..:||::.|...|:||.:|.::...:.|:|..|
Mouse   435 KPLDMIVGKAWNMFSSKAFIHQYTKFGMEEEDFLDSFALLEQVVASY 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	115/502 (23%)
CG7794	NP_650674.1	PTZ00335	6..439	CDD:185562	115/502 (23%)
Tubd1	NP_001185974.1	delta_zeta_tubulin-like	2..483	CDD:276958	115/502 (23%)
Tubd1	NP_001185974.1	Tubulin	2..213	CDD:278518	57/217 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900