DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7794 and tuba4b

DIOPT Version :9

Sequence 1:	NP_650674.1	Gene:	CG7794 / 42159	FlyBaseID:	FBgn0038565	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	XP_012825888.1	Gene:	tuba4b / 549448	XenbaseID:	XB-GENE-489927	Length:	452	Species:	Xenopus tropicalis

Alignment Length:	451	Identity:	236/451 - (52%)
Similarity:	317/451 - (70%)	Gaps:	9/451 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRL----TQSPMDDSFLTFFEFTSHQPCVQPRLV 66
            |.|.:|:||||||:.||||||:||||||..:|::    |....||||.|||..|.....| ||.|
Frog     6 ECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFSETGAGKHV-PRAV 69

  Fly    67 MIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRCRN 131
            .:|.|||||||:|.|:||.||||:.|||||:|:.:|:|||:..:..|::|..::.||::||:|..
Frog    70 FVDLEPTVIDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLADQCTG 134

  Fly   132 LRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHFSM 196
            |:|||||.:.|||:|||..:.:||||..|:||| :.:||.:||:|.:|..:|||||::|..|.::
Frog   135 LQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKK-SKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 198

  Fly   197 DCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTNLV 261
            :.:|.:|:|||||:||||...|::..||||||||:|:|:|||.|||.||.|...|...|.|||||
Frog   199 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLV 263

  Fly   262 PYPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDIAP 326
            ||||||:||..|||::....:....:|.:::|..||:.:||||:|:|.||||||..||||||:.|
Frog   264 PYPRIHFPLATYAPVISAEKAYHEQLSVSEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVP 328

  Fly   327 NEINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAWCR 391
            .::|.|:..||..|:.:||||.|||||:|::..||..|||||||...||...:||.|.|..||.|
Frog   329 KDVNAAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTAVPGGDLAKVQRAVCMLSNTTAIAEAWAR 393

  Fly   392 LVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEVDASAPTSRRDSDPEED 452
            |.:|||.:|.:||||:.|||||:|||.|:||.|::..|..||.||...   |..|.|..|:
Frog   394 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGID---SYEDEDEGEE 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	230/433 (53%)
CG7794	NP_650674.1	PTZ00335	6..439	CDD:185562	232/436 (53%)
tuba4b	XP_012825888.1	PTZ00335	5..442	CDD:185562	232/440 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D514396at2759
OrthoFinder	1	1.000	-	-		FOG0000082
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920