DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7794 and tubb3

DIOPT Version :9

Sequence 1:	NP_650674.1	Gene:	CG7794 / 42159	FlyBaseID:	FBgn0038565	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_989408.1	Gene:	tubb3 / 395045	XenbaseID:	XB-GENE-5886292	Length:	449	Species:	Xenopus tropicalis

Alignment Length:	457	Identity:	158/457 - (34%)
Similarity:	261/457 - (57%)	Gaps:	24/457 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRLTQSPMDDSFLT-------FFEFTSHQPCVQP 63
            ||:.|..||.|.||....||:...||||...|..    :.||.|.       :.|.:||:  ..|
Frog     3 EIVHIQAGQCGNQIGAKFWEVISDEHGIDPCGNY----IGDSDLQLERISVYYNEASSHK--YVP 61

  Fly    64 RLVMIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADR 128
            |.:::|.||..:|.:|:|::.:||.||..|.|:..:|:|:|:|:....:||:|..::.:|:..:.
Frog    62 RAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECEN 126

  Fly   129 CRNLRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAH 193
            |..|:||.:..::|||:|||:||.::.::.|::..:: :..|.|.|||.:|..:||||||.|:.|
Frog   127 CDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRI-MNTFSVVPSPKVSDTVVEPYNATLSIH 190

  Fly   194 FSMDCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQT 258
            ..::..|.::.:|||||||||..||.:..|||.:||.:::..:|..|.|.||.|......::|..
Frog   191 QLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAV 255

  Fly   259 NLVPYPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGD 323
            |:||:||:|:.:..:|||......|:..::..:||.|.|...|.|..|:|.||:|:....::||.
Frog   256 NMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGR 320

  Fly   324 IAPNEINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIA 388
            ::..|::..:..|:...|..||:|.|...|:.|..:||   .|..::.|     .|.|:|.|:..
Frog   321 MSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPP---RGLKMSST-----FIGNSTAIQEL 377

  Fly   389 WCRLVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEV-DASA-PTSRRDSDPEE 451
            :.|:..:|..:::|:||::.|.|||::|..|.||..|:..||.:|.:. ||:| .......|.||
Frog   378 FKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDEE 442

  Fly   452 DS 453
            :|
Frog   443 ES 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	151/436 (35%)
CG7794	NP_650674.1	PTZ00335	6..439	CDD:185562	152/440 (35%)
tubb3	NP_989408.1	PLN00220	1..447	CDD:215107	158/457 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910