DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7794 and tubb2b

DIOPT Version :9

Sequence 1:	NP_650674.1	Gene:	CG7794 / 42159	FlyBaseID:	FBgn0038565	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_989275.1	Gene:	tubb2b / 394889	XenbaseID:	XB-GENE-491121	Length:	445	Species:	Xenopus tropicalis

Alignment Length:	453	Identity:	151/453 - (33%)
Similarity:	255/453 - (56%)	Gaps:	22/453 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRLTQSPMDDSFLT-------FFEFTSHQPCVQP 63
            ||:.|..||.|.||....||:...||||...|    |...||.|.       :.|.|.::  ..|
Frog     3 EIVHIQAGQCGNQIGAKFWEVISDEHGIDPTG----SYHGDSDLQLERINVYYNEATGNK--FVP 61

  Fly    64 RLVMIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADR 128
            |.:::|.||..:|.:|:|.:..:|.||..:.|:..:|:|:|:|:....:||:|..::.:|:.|:.
Frog    62 RAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAES 126

  Fly   129 CRNLRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAH 193
            |..|:||.:..::|||:|||:||.::.::.|::..:: :..|.|.|||.:|..:||||||.|:.|
Frog   127 CDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRI-MNTFSVMPSPKVSDTVVEPYNATLSVH 190

  Fly   194 FSMDCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQT 258
            ..::..|.::.:|||||||||..||.:..|||.:||.:::..:|..|...||.|......::|..
Frog   191 QLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAV 255

  Fly   259 NLVPYPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGD 323
            |:||:||:|:.:..:|||......|:..::..:||.|.|...|.|..|:|.||:|:....::||.
Frog   256 NMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGR 320

  Fly   324 IAPNEINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIA 388
            ::..|::..:.|::...|..||:|.|...|..|..:||   .|..::.|     .|.|:|.|:..
Frog   321 MSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMSAT-----FIGNSTAIQEL 377

  Fly   389 WCRLVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEVDASAPTSRRDSDPEE 451
            :.|:..:|..:::|:||::.|.|||::|..|.||..|:..||.:|.:...:....:.:.:.||
Frog   378 FKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEE 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	149/436 (34%)
CG7794	NP_650674.1	PTZ00335	6..439	CDD:185562	149/439 (34%)
tubb2b	NP_989275.1	PLN00220	1..430	CDD:215107	149/441 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910