DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7794 and Tube1

DIOPT Version :9

Sequence 1:	NP_650674.1	Gene:	CG7794 / 42159	FlyBaseID:	FBgn0038565	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	XP_006256590.1	Gene:	Tube1 / 361856	RGDID:	1306048	Length:	475	Species:	Rattus norvegicus

Alignment Length:	475	Identity:	135/475 - (28%)
Similarity:	241/475 - (50%)	Gaps:	62/475 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 IQIHIGQAGVQIANACWELFCLEHGILANGRLTQSPMDDSFLTFFEFTSHQ---PC--------- 60
            :.:.:||.|.||....|:|...||..:..    :...||:..:||.....:   .|
  Rat     5 VVVQVGQCGNQIGCCFWDLALREHAAVNQ----KGIYDDAISSFFRNVDTRAVGDCGSISKGRIS 65

  Fly    61 -VQPRLVMIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRR 124
             ::.|.|:||.|..|::||..|..|::|....|||....||:|:|.|:.:..|...::.:..:|:
  Rat    66 SLKARAVLIDMEEGVVNEILQGPLRDVFDSKQLITDISGSGNNWAVGHKVFGSLYREQILEKLRK 130

  Fly   125 VADRCRNLRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFL--VYPSPSISPVIVEPYN 187
            .|:.|..|:.|.:..::|||:||||||.:::.|.::|.:   |..|:  |||| |...||..|||
  Rat   131 SAEHCDCLQCFFIIHSMGGGTGSGLGTFLLKVLEDEFPE---VYRFVTAVYPS-SEDDVITSPYN 191

  Fly   188 ALLAAHFSMDCADVSFIVDNEALYDICAN--------------------TLNVPAPT-------Y 225
            ::||.....:.||....:||::|:||.:.                    |.|. .|.       :
  Rat   192 SMLAMKELSEHADCVLPIDNQSLFDIISKIDLVVNSGKLGSAVKPKSLITSNT-GPVKKRHKKPF 255

  Fly   226 TNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTNLVPYPRIHYPLINYAPLVPISHSQFVNMSTA 290
            ..:|.|:|.::.|.|:|.||.|...:...|:..||||:|::||.:.:..||..::..........
  Rat   256 DAMNNIVANLLLSLTSSARFEGSLNMDLNEISMNLVPFPQLHYLVSSLTPLYTLADVNIPPRRLD 320

  Fly   291 QLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDIAPNEINTALENIKRNRSFRFVDWSPTGFKIG 355
            |:....|...:|:::.:|.||.|:|..|:.||::..:::...:|.:|  .:.:||.|:..|:|..
  Rat   321 QMFSDAFSKGHQLLQADPRHGLYLACALIVRGEVQISDLRRNIERLK--PALQFVSWNQEGWKTS 383

  Fly   356 VSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAWCRLVNKFDKLYQRRAFVYHYVG-EGLEEGNF 419
            :..:||...|        .:.:|::|||.::..:..|..:|.:||:::|.::||:. :|:||..|
  Rat   384 LCSVPPVGHP--------HSLLALANNTCVKPTFLELRERFMRLYKKKAHLHHYLQVDGMEESTF 440

  Fly   420 NEASENICQLVHDYLEVDAS 439
            .||..::..|:.:|.::||:
  Rat   441 TEAVSSLSALIQEYSDLDAT 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	133/470 (28%)
CG7794	NP_650674.1	PTZ00335	6..439	CDD:185562	134/473 (28%)
Tube1	XP_006256590.1	PTZ00387	1..470	CDD:240395	135/475 (28%)
Tube1	XP_006256590.1	epsilon_tubulin	2..457	CDD:276959	133/470 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900