Protein Alignment CG7794 and TUBB8

DIOPT Version :9

• Sequence 1: NP_650674.1
• Gene: CG7794 / 42159
• FlyBaseID: FBgn0038565
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_817124.1
• Gene: TUBB8 / 347688
• HGNCID: 20773
• Length: 444
• Species: Homo sapiens
• Alignment Length: 454
• Identity: 159/454 - (35%)
• Similarity: 259/454 - (57%)
• Gaps: 21/454 - (4%)

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRLTQSPMDDSFL------TFFEFTSHQPCVQPR 64
            ||:...|||.|.||....||:...||.|.:.|    :...||.|      .::...|....| ||
Human     3 EIVLTQIGQCGNQIGAKFWEVISDEHAIDSAG----TYHGDSHLQLERINVYYNEASGGRYV-PR 62

  Fly    65 LVMIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRC 129
            .|::|.||..:|.:|:|.:..:|.||..|.|:..:|:|:|:|:....:||::..|:.:|:.|:.|
Human    63 AVLVDLEPGTMDSVRSGPFGQVFRPDNFIFGQCGAGNNWAKGHYTEGAELMESVMDVVRKEAESC 127

  Fly   130 RNLRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHF 194
            ..|:||.:..::|||:|||:||.::.::.|::..:: :..|.:.|||.:|..:||||||.|:.|.
Human   128 DCLQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRI-INTFSILPSPKVSDTVVEPYNATLSVHQ 191

  Fly   195 SMDCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTN 259
            .::.||.:|.:|||||||||:.||.:|.|||.:||.:::..:|..|...||.|......::|..|
Human   192 LIENADETFCIDNEALYDICSKTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVN 256

  Fly   260 LVPYPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDI 324
            :||:||:|:.:..:|||......|:..::.|:||.|.|...|.|..|:|.||:|:.:..::||.:
Human   257 MVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMMAACDPRHGRYLTAAAIFRGRM 321

  Fly   325 APNEINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAW 389
            ...|::..:.||:...|..|.||.|...|..|..:||   .|..::.|     .|.|||.|:..:
Human   322 PMREVDEQMFNIQDKNSSYFADWLPNNVKTAVCDIPP---RGLKMSAT-----FIGNNTAIQELF 378

  Fly   390 CRLVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEV-DASAPTSRRDSDPEED 452
            .|:..:|..:::|:||::.|.|||::|..|.||..|:..||.:|.:. ||:|.....:...||:
Human   379 KRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDEEYAEEE 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	154/435 (35%)
		PTZ00335	6..439	CDD:185562	155/439 (35%)
TUBB8	NP_817124.1	PTZ00010	1..427	CDD:240228	154/437 (35%)
		beta_tubulin	2..426	CDD:276956	154/436 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	423..444		5/20 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810