DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7794 and tuba4l

DIOPT Version :9

Sequence 1:	NP_650674.1	Gene:	CG7794 / 42159	FlyBaseID:	FBgn0038565	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_956089.1	Gene:	tuba4l / 327377	ZFINID:	ZDB-GENE-030131-5588	Length:	449	Species:	Danio rerio

Alignment Length:	449	Identity:	233/449 - (51%)
Similarity:	316/449 - (70%)	Gaps:	6/449 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRL---TQSPMDDSFLTFFEFTSHQPCVQPRLVM 67
            |.|.|||||||:|:.|:||||:|||||...:|.:   ::|..|.||.|||..|.....| ||.|.
Zfish     3 ECISIHIGQAGIQMGNSCWELYCLEHGFQPDGTIVDSSRSLADSSFGTFFSETGAGKYV-PRAVF 66

  Fly    68 IDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRCRNL 132
            ||.||||:||||.|.||.|:||:.||:||:|:.:|:|||:..:..|::|..::.:|::||:|..|
Zfish    67 IDLEPTVVDEIRNGHYRQLYHPEQLISGKEDAANNYARGHYTIGKEIVDSVLDRMRKMADQCTGL 131

  Fly   133 RGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHFSMD 197
            :|||:|.:.|||:|||..:.:||||..|:||| :.:||.|||:|.:|..:|||||::|..|.:::
Zfish   132 QGFLIFHSFGGGTGSGFTSLLMERLSVDYGKK-SKLEFSVYPAPQVSTAVVEPYNSILTTHTTLE 195

  Fly   198 CADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTNLVP 262
            .:|.||:|||||::|||...|::..|:||||||:|||:|||.|||.||.|...|...|.||||||
Zfish   196 HSDCSFMVDNEAIFDICKRNLDIERPSYTNLNRLIAQIVSSITASLRFDGALNVDLTEFQTNLVP 260

  Fly   263 YPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDIAPN 327
            |||||:||:.|:|::....:....:|..::|..||:.:||||:|:|..|||||..||||||:.|.
Zfish   261 YPRIHFPLVTYSPIISAEKAYHEQLSVPEITNACFEPANQMVKCDPRRGKYMACCLLYRGDVVPK 325

  Fly   328 EINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAWCRL 392
            ::|.|:.|||..||.:||||.|||||:|::..||..|||||||...||...:||.|.|..||.||
Zfish   326 DVNAAIANIKTRRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWGRL 390

  Fly   393 VNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEVDASAPTSRRDSDPEE 451
            .:|||.:|.:||||:.|||||:|||.|:||.|::..|..||.||.|.: |.....|.||
Zfish   391 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVAADS-TDDCGEDEEE 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	226/432 (52%)
CG7794	NP_650674.1	PTZ00335	6..439	CDD:185562	228/435 (52%)
tuba4l	NP_956089.1	PTZ00335	1..449	CDD:185562	233/449 (52%)
tuba4l	NP_956089.1	alpha_tubulin	2..434	CDD:276955	226/432 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D514396at2759
OrthoFinder	1	1.000	-	-		FOG0000082
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.870