DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7794 and Tuba4a

DIOPT Version :9

Sequence 1:	NP_650674.1	Gene:	CG7794 / 42159	FlyBaseID:	FBgn0038565	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001007005.1	Gene:	Tuba4a / 316531	RGDID:	1359623	Length:	448	Species:	Rattus norvegicus

Alignment Length:	451	Identity:	238/451 - (52%)
Similarity:	316/451 - (70%)	Gaps:	9/451 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRL----TQSPMDDSFLTFFEFTSHQPCVQPRLV 66
            |.|.:|:||||||:.||||||:||||||..:|::    |....||||.|||..|.....| ||.|
  Rat     3 ECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHV-PRAV 66

  Fly    67 MIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRCRN 131
            .:|.|||||||||.|.||.||||:.|||||:|:.:|:|||:..:..|::|..::.||:::|:|..
  Rat    67 FVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLSDQCTG 131

  Fly   132 LRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHFSM 196
            |:|||||.:.|||:|||..:.:||||..|:||| :.:||.:||:|.:|..:|||||::|..|.::
  Rat   132 LQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKK-SKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 195

  Fly   197 DCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTNLV 261
            :.:|.:|:|||||:||||...|::..||||||||:|:|:|||.|||.||.|...|...|.|||||
  Rat   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLV 260

  Fly   262 PYPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDIAP 326
            ||||||:||..|||::....:....:|.|::|..||:.:||||:|:|.||||||..||||||:.|
  Rat   261 PYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVP 325

  Fly   327 NEINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAWCR 391
            .::|.|:..||..||.:||||.|||||:|::..||..|||||||...||...:||.|.|..||.|
  Rat   326 KDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390

  Fly   392 LVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEVDASAPTSRRDSDPEED 452
            |.:|||.:|.:||||:.|||||:|||.|:||.|::..|..||.||...   |..|.|..|:
  Rat   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGID---SYEDEDEGEE 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	232/433 (54%)
CG7794	NP_650674.1	PTZ00335	6..439	CDD:185562	234/436 (54%)
Tuba4a	NP_001007005.1	PTZ00335	1..448	CDD:185562	237/449 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D514396at2759
OrthoFinder	1	1.000	-	-		FOG0000082
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910