DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7794 and Tubb6

DIOPT Version :9

Sequence 1:	NP_650674.1	Gene:	CG7794 / 42159	FlyBaseID:	FBgn0038565	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001020846.1	Gene:	Tubb6 / 307351	RGDID:	1305887	Length:	447	Species:	Rattus norvegicus

Alignment Length:	453	Identity:	151/453 - (33%)
Similarity:	256/453 - (56%)	Gaps:	12/453 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGI-LANGRLTQSPMDDSFLTFFEFTSHQPCVQPRLVMID 69
            ||:.|..||.|.||....||:...|||| .|.|.:..|.:....::.:...|......||..::|
  Rat     3 EIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERISVYYNESSSKKYVPRAALVD 67

  Fly    70 TEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRCRNLRG 134
            .||..:|.:|:|.:..||.||..|.|:..:|:|:|:|:....:||:|..::.:|:..:.|..|:|
  Rat    68 LEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDSVLDVVRKECEHCDCLQG 132

  Fly   135 FLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHFSMDCA 199
            |.:..::|||:|||:||.::.::.|::..:: :..|.|.|||.:|..:||||||.|:.|..::..
  Rat   133 FQLTHSLGGGTGSGMGTLLISKIREEYPDRI-MNTFSVMPSPKVSDTVVEPYNATLSVHQLVENT 196

  Fly   200 DVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTNLVPYP 264
            |.::.:|||||||||..||.:..|||.:||.:::..:|..|.|.||.|......::|..|:||:|
  Rat   197 DETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFP 261

  Fly   265 RIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDIAPNEI 329
            |:|:.:..:|||......|:..::..:||.|.|...|.|..|:|.||:|:....::||.::..|:
  Rat   262 RLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGPMSMKEV 326

  Fly   330 NTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAWCRLVN 394
            :..:..|:...|..||:|.|...|:.|..:||   .|..:|.|     .|.|:|.|:..:.|:..
  Rat   327 DEQMLAIQNKNSSYFVEWIPNNVKVAVCDIPP---RGLKMAST-----FIGNSTAIQELFKRISE 383

  Fly   395 KFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEVDASAPTSRRDS--DPEEDSLN 455
            :|..:::|:||::.:.|||::|..|.||..|:..||.:|.:...:......::  |.:|:.:|
  Rat   384 QFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVSEYQQYQDATVNDGEEAFEDEDEEEIN 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	148/430 (34%)
CG7794	NP_650674.1	PTZ00335	6..439	CDD:185562	148/433 (34%)
Tubb6	NP_001020846.1	PLN00220	1..431	CDD:215107	148/436 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900