Protein Alignment CG7794 and TUBB

DIOPT Version :9

• Sequence 1: NP_650674.1
• Gene: CG7794 / 42159
• FlyBaseID: FBgn0038565
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001280141.1
• Gene: TUBB / 203068
• HGNCID: 20778
• Length: 464
• Species: Homo sapiens
• Alignment Length: 456
• Identity: 149/456 - (32%)
• Similarity: 255/456 - (55%)
• Gaps: 29/456 - (6%)

  Fly     8 IQIHIGQAGVQIANAC-------WELFCLEHGILANGRL---TQSPMDDSFLTFFEFTSHQPCVQ 62
            ::.|.||....:.:|.       ||:...||||...|..   :...:|...:.:.|.|..:  ..
Human    18 VRDHPGQQSETLPHATFLQKIKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGK--YV 80

  Fly    63 PRLVMIDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVAD 127
            ||.:::|.||..:|.:|:|.:..:|.||..:.|:..:|:|:|:|:....:||:|..::.:|:.|:
Human    81 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAE 145

  Fly   128 RCRNLRGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAA 192
            .|..|:||.:..::|||:|||:||.::.::.|::..:: :..|.|.|||.:|..:||||||.|:.
Human   146 SCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRI-MNTFSVVPSPKVSDTVVEPYNATLSV 209

  Fly   193 HFSMDCADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQ 257
            |..::..|.::.:|||||||||..||.:..|||.:||.:::..:|..|...||.|......::|.
Human   210 HQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLA 274

  Fly   258 TNLVPYPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRG 322
            .|:||:||:|:.:..:|||......|:..::..:||.|.|...|.|..|:|.||:|:....::||
Human   275 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRG 339

  Fly   323 DIAPNEINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRI 387
            .::..|::..:.|::...|..||:|.|...|..|..:||   .|..:|.|     .|.|:|.|:.
Human   340 RMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMAVT-----FIGNSTAIQE 396

  Fly   388 AWCRLVNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEV-DASAPTSRRDSDPEE 451
            .:.|:..:|..:::|:||::.|.|||::|..|.||..|:..||.:|.:. ||:|       :.||
Human   397 LFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA-------EEEE 454

  Fly   452 D 452
            |
Human   455 D 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	143/437 (33%)
		PTZ00335	6..439	CDD:185562	144/441 (33%)
TUBB	NP_001280141.1	PLN00220	39..449	CDD:215107	140/420 (33%)
		beta_tubulin	39..446	CDD:276956	139/417 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810